Dr. Owen Ko

HKD 3,926,000

Development and Preclinical Test of Optical Pumping-based Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging for Diagnosis of Neurological Diseases

Partnership Research Programme, Innovation and Technology Fund of the Innovation and Technology Commission of Hong Kong

2022 - 2025

Prof. Vincent Mok

HKD 1,154,476

Progression of prodromal markers of α-synucleinopathy neurodegeneration in the first-degree relatives of patients with REM sleep behavior disorder: a 7-year prospective study

General Research Fund, University Grants Committee

2021 - 2024

Prof. Vincent Mok

HKD 1,112,120

Neural correlates of impulsivity in idiopathic REM sleep behavior disorder: a functional Magnetic Resonance Imaging case-control study

Health and Medical Research Fund, Hong Kong Food and Health Bureau

2021 - 2024

Dr. Owen Ko

RMB 2,000,000

Anti-aging Effects of GLP-1R Agonism and Companion Non-invasive Diagnostics

Excellent Young Scientists Fund (Hong Kong and Macau), National Natural Science Foundation of China

2021 - 2024

Dr. Owen Ko

RMB 1,000,000

Development of Novel Therapeutics Drug for Niemann-Pick Disease, Type C

Science, Technology and Innovation Commission of Shenzhen Municipality

2021 - 2024

Dr. Owen Ko

HKD 4,700,000

Clearing the Way for Better Tissue Diagnostics - a Midstream Development Project on Accessible Three-dimensional Histology Methods and Platform

Midstream Research Programme, Hong Kong Innovation and Technology Council

2021 - 2024

Prof. Vincent Mok

HKD 1,104,304

Gut microbiota in major depressive disorders with and without Rapid Eye Movement Behavior Disorder: tracing a subtype of depression with underlying neurodegeneration

Health and Medical Research Fund, Hong Kong Food and Health Bureau

2021 - 2023

Prof. Vincent Mok

HKD 1,338,540

Development and Clinical Application of Early Warning Platform for Cognitive Impairment in Parkinson’s Disease

Guangdong-Hong Kong Technology Cooperation Funding Scheme, Innovation and Technology Commission

2021 - 2023

Dr. Owen Ko

HKD 911,140

Novel MRI-based Machine Learning Tool to Detect Mild Cognitive Impairment Associated with Alzheimer’s Disease

Health and Medical Research Fund, Hong Kong Food and Health Bureau

2021 - 2023

Dr. Owen Ko

HKD 965,803

A Comprehensive Survey on Alpha-Synuclein Pathologies in Colonic Submucosal Biopsies of Prodromal Parkinson’s Disease Patients – An Exploratory Study

Health and Medical Research Fund, Hong Kong Food and Health Bureau

2021 - 2023

Dr. Owen Ko

HKD 1,063,000

Construction of a MesoSPIM Light Sheet Microscope

Academic Equipment Grant, CUHK

2021

Dr. Karen Ma

HKD 200,000

Neuroimaging Biomarkers in Parkinsonian Syndromes

Hong Kong Neurological Society Research Grant, Hong Kong Neurological Society

2021

Dr. Bonaventure Ip

Young Investigator Research Grant, The Hong Kong College of Physicians

2021

Aerobic exercise in older people with subclinical sporadic cerebral small vessel disease: A randomized clinical trial

WONG A, LAM BYK, MAK MKY, LAM LCW, AU LWC, YIU BKF, WONG C, TONG HY, YEUNG SK, CHU WCW, SHI L, LEUNG TWH, SOO YOY, LAU AYL, IP BYM, KWOK TCY, KO H, MOK VCT.

Alzheimer’s Dement. 2021;7:e12224.

Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion

Nie X, Wang D, Pu Y, Wei Y, Lu Q, Yan H, Liu X, Zheng L, Liu J, Yang X, Ding Y, Liu D, Duan W, Zhang Z, Yang Z, Wen M, Gu W, Hou X, Leng X, Pan Y, Miao Z, Liu L(corresponding author)

Stroke Vasc Neurol. 2021;0. doi:10.1136/ svn-2021-001242

Neurovascular ageing: transcriptomic readout and implications on therapeutic targeting in Alzheimer's disease

Li Z, Ip B, Mok VCT, Ko H

Neural Regen Res. 2021 Dec;16(12):2411-2412. doi: 10.4103/1673-5374.313042.

Diffusion MRI harmonization enables joint-analysis of multicentre data of patients with cerebral small vessel disease

de Brito Robalo BM, Biessels GJ, Chen C, Dewenter A, Duering M, Hilal S, Koek HL, Kopczak A, Yin Ka Lam B, Leemans A, Mok V, Onkenhout LP, van den Brink H, de Luca A.

Neuroimage Clin. 2021;32:102886. doi: 10.1016/j.nicl.2021.102886.

Cricopharyngeal peroral endoscopic myotomy improves oropharyngeal dysphagia in patients with Parkinson's disease

Wu PI, Szczesniak MM, Omari T, Lam TY, Wong M, Maclean J, Ma KK, Chan AY, Mok V, Cook IJ, Cock C, Sung J, Wu J, Chiu PW

Endosc Int Open. 2021 Nov 12;9(11):E1811-E1819. doi: 10.1055/a-1562-7107. PMID: 34790549; PMCID: PMC8589553.

Prevalence and correlates of REM sleep behaviour disorder in patients with major depressive disorder: a two-phase study

Wang J; Chau SWH, Lam SP, Liu YP, Zhang JH, Chan NY, Cheung MMS, Yu MWM, Tsang JCT, Chan JWY, Huang B, Li SX, Mok V, Wing YK

Journal of Neurology Neurosurgery and Psychiatry. 11 Nov 2021.

The state of stroke services across the globe: Report of World Stroke Organization-World Health Organization surveys

Owolabi MO, Thrift AG, Martins S, Johnson W, Pandian J, Abd-Allah F, Varghese C, Mahal A, Yaria J, Phan HT, Roth G, Gall SL, Beare R, Phan TG, Mikulik R, Norrving B, Feigin VL; Stroke Experts Collaboration Group

Int J Stroke. 2021 Oct;16(8):889-901. doi: 10.1177/17474930211019568.

Magnetic navigation of collective cell microrobots in blood under ultrasound Doppler imaging

Wang Q, Tian Y, Du X, Ko H, Ip BYM, Leung TWH, Yu SCH, Zhang L

IEEE/ASME Transactions on Mechatronics. 2021 Sep 23; (99):1-12. doi:10.1109/TMECH.2021.3109346.

Comparison of Newtonian and Non-newtonian Fluid Models in Blood Flow Simulation in Patients With Intracranial Arterial Stenosis

Liu H, Lan L, Abrigo J, Ip HL, Soo Y, Zheng D, Wong KS, Wang D, Shi L, Leung TW, Leng X

Front Physiol. 2021 Sep 6;12:718540. doi: 10.3389/fphys.2021.718540.

Deep-Learning-Based Pre-Diagnosis Assessment Module for Retinal Photographs: A Multicenter Study

Yuen V, Ran A, Shi J, Sham K, Yang D, Chan VTT, Chan R, Yam JC, Tham CC, McKay GJ, Williams MA, Schmetterer L, Cheng CY, Mok V, Chen CL, Wong TY, Cheung CY

Transl Vis Sci Technol. 2021 Sep 1;10(11):16. doi: 10.1167/tvst.10.11.16. PMID: 34524409; PMCID: PMC8444486.

Reconfigurable magnetic microswarm for accelerating tPA-mediated thrombolysis under ultrasound imaging

Wang Q, Jin D, Wang B, Xia N, Ko H, Ip BYM, Leung TWH, Yu SCH, Zhang L

IEEE/ASME Transactions on Mechatronics. 2021 Aug 11;doi:10.1109/TMECH.2021.3103994.

International Survey of Mechanical Thrombectomy Stroke Systems of Care During COVID-19 Pandemic

Yavagal DR, Saini V, Inoa V, Gardener HE, Martins SO, Fakey M, Ortega S, Mansour O, Leung T, Al-Mufti F, Jadhav AP, Potter-Vig J, Mairal A, Zhongrong M, Sylaja PN, Demchuk AM; MT2020 Global Executive Committee

J Stroke Cerebrovasc Dis. 2021 Aug;30(8):105806. doi: 10.1016/j.jstrokecerebrovasdis.2021.105806.

Understanding the Clinical Implications of Intracranial Arterial Calcification Using Brain CT and Vessel Wall Imaging

Yang WJ, Wasserman BA, Zheng L, Huang ZQ, Li J, Abrigo J, Wong SS, Ying MT, Chu WC, Wong LK, Leung TW and Chen XY.

Front Neurol . 15 July 2021. DOI: 10.3389/fneur.2021.619233.

Global impact of COVID-19 on stroke care

Nogueira RG … Leung T… Nguyen TN.

Int J Stroke. . 2021 Jul;16(5):573-584. doi: 10.1177/1747493021991652

A prediction of hematoma expansion in hemorrhagic patients using a novel dual-modal machine learning strategy

Cheng X, Zhang W, Wu ML, Jiang N, Guo ZN, Leng X, Song JN, Jin H, Sun X, Zhang F, Qin J, Yan X, Cai Z, Luo Y, Yang Y, Liu J

Physiol Meas. 2021 Jul 1. doi: 10.1088/1361-6579/ac10ab. Online ahead of print.

Retinal imaging in Alzheimer’s disease

Cheung CY, Mok V, Foster PJ, Trucco E, Chen C, Wong TY

J Neurol Neurosurg Psychiatry . 2021;92:983–994.

Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

Nogueira RG … Leung T… Nguyen TN.

Neurology. 2021 Jun 8;96(23):e2824-e2838. doi: 10.1212/WNL.0000000000011885.

Machine-learning method for localization of cerebral white matter hyperintensities in healthy adults based on retinal images

Zee B, Wong Y, Lee J, Fan Y, Zeng J, Lam B, Wong A, Shi L, Lee A, Kwok C, Lai M, Mok V, Lau A

Brain Commun. 2021 Jun 3;3(3):fcab124. doi: 10.1093/braincomms/fcab124. PMID: 34222872; PMCID: PMC8249101.

Systemic GLP-1R agonist treatment reverses mouse glial and neurovascular cell transcriptomic aging signatures in a genome-wide manner

Li Z, Chen X, Vong JSL, Zhao L, Huang J, Yan LYC, Ip B, Wing YK, Lai HM, Mok VCT, Ko H

Communications Biology. 2021 Jun 2;4(1)656.

High burden of cerebral white matter lesion in 9 Asian cities

Lam BYK, Yiu B, Ampil E, Chen CL, Dikot Y, Dominguez JC, Ganeshbhai PV, Hilal S, Kandiah N, Kim S, Lee JY, Ong AP, Senanarong V, Leung KT, Wang H, Yang YH, Yong T, Arshad F, Alladi S, Wong S, Ko H, Lau AYL, Mok VCT

Sci Rep. 2021 Jun 2;11(1):11587. doi: 10.1038/s41598-021-90746-x.

Quantitative Susceptibility Mapping of the Hippocampal Fimbria in Alzheimer's Disease

Au CKF, Abrigo J, Liu C, Liu W, Lee J, Au LWC, Chan Q, Chen S, Leung EYL, Ho CL, Ko H, Mok VCT, Chen W

J Magn Reson Imaging. 2021 Jun;53(6):1823-1832. doi: 10.1002/jmri.27464.

Super-refractory status epilepticus in autoimmune encephalitis treated with interleukin-1 receptor antagonist, anakinra

Choi CH, Ma SH, Ma KK, Leung H, Mok VC

Epileptic Disord. 2021 Jun 1;23(3):500-505. doi: 10.1684/epd.2021.1283.

Validation of a translated Chinese version of the Participation Strategies Self-Efficacy Scale: a cross-sectional study

Chau JPC, Lo SHS, Zhao J, Choi KC, Lam SKY, Saran R, Shi J, Thompson DR, Lau AYL

Disabil Rehabil. 2021 Jun 1:1-7. doi: 10.1080/09638288.2021.1933220.

Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts

Weaver NA, Kuijf HJ, Aben HP, Abrigo J, Bae HJ, Barbay M, Best JG, Bordet R, Chappell FM, Chen CPLH, Dondaine T, van der Giessen RS, Godefroy O, Gyanwali B, Hamilton OKL, Hilal S, Huenges Wajer IMC, Kang Y, Kappelle LJ, Kim BJ, Köhler S, de Kort PLM, Koudstaal PJ, Kuchcinski G, Lam BYK, Lee BC, Lee KJ, Lim JS, Lopes R, Makin SDJ, Mendyk AM, Mok VCT, Oh MS, van Oostenbrugge RJ, Roussel M, Shi L, Staals J, Del C Valdés-Hernández M, Venketasubramanian N, Verhey FRJ, Wardlaw JM, Werring DJ, Xin X, Yu KH, van Zandvoort MJE, Zhao L, Biesbroek JM, Biessels GJ

Lancet Neurol. 2021 Jun;20(6):448-459. doi: 10.1016/S1474-4422(21)00060-0.

Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir

Lo HS, Hui KPY, Lai HM, He X, Khan KS, Kaur S, Huang J, Li Z, Chan AKN, Cheung HH, Ng KC, Ho JCW, Chen YW, Ma B, Cheung PM, Shin D, Wang K, Lee MH, Selisko B, Eydoux C, Guillemot JC, Canard B, Wu KP, Liang PH, Dikic I, Zuo Z, Chan FKL, Hui DSC, Mok VCT, Wong KB, Mok CKP, Ko H, Aik WS, Chan MCW, Ng WL

ACS Cent Sci. 2021 May 26;7(5):792-802. doi: 10.1021/acscentsci.0c01186.

MRI-based Alzheimer's disease-resemblance atrophy index in the detection of preclinical and prodromal Alzheimer's disease

Liu W, Au LWC, Abrigo J, Luo Y, Wong A, Lam BYK, Fan X, Kwan PWL, Ma HW, Ng AYT, Chen S, Leung EYL, Ho CL, Wong SHM, Chu WC, Ko H, Lau AYL, Shi L, Mok VCT; Alzheimer’s Disease Neuroimaging Initiative

Aging (Albany NY). 2021 May 25;13(10):13496-13514. doi: 10.18632/aging.203082. . https://pubmed.ncbi.nlm.nih.gov/34091443/

Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging

Jiang Y, Zhou X, Ip FC, Chan P, Chen Y, Lai NCH, Cheung K, Lo RMN, Tong EPS, Wong BWY, Chan ALT, Mok VCT, Kwok TCY, Mok KY, Hardy J, Zetterberg H, Fu AKY, Ip NY

Alzheimers Dement. 2021 May 25. doi: 10.1002/alz.12369.

Erratum

Mok VCT, Pendlebury S, Wong A, Alladi S, Au L, Bath PM, Biessels GJ, Chen C, Cordonnier C, Dichgans M, Dominguez J, Gorelick PB, Kim S, Kwok T, Greenberg SM, Jia J, Kalaria R, Kivipelto M, Naegandran K, Lam LCW, Lam BYK, Lee ATC, Markus HS, O'Brien J, Pai MC, Pantoni L, Sachdev P, Senanarong V, Skoog I, Smith EE, Srikanth V, Suh GH, Wardlaw J, Ko H, Black SE, Scheltens P

Alzheimers Dement. 2021 May;17(5):906-907. doi: 10.1002/alz.12307.

Neurological diseases and risk of mortality in patients with COVID-19 and SARS: a territory-wide study in Hong Kong

Fan FSY, Yip TCF, Yiu B, Lam B, Au L, Lau AYL, Ip B, Soo Y, Leung TWH, Li T, Lui G, Wong GLH, Mok VCT

J Neurol Neurosurg Psychiatry. 2021 Apr 27;jnnp-2021-326286.

The Use of Cabozantinib in Advanced Hepatocellular Carcinoma in Hong Kong-A Territory-Wide Cohort Study

Wong JS, Dong Y, Tang V, Leung T, Yeung CSY, Tai A, Law A, Shum T, Kwok GG, Li BC, Leung R, Chiu J, Ma KW, She WH, Tsang J, Cheung TT, Yau T

Cancers (Basel). 2021 Apr 21;13(9):2002. doi: 10.3390/cancers13092002.

Elevated Neutrophil to Lymphocyte Ratio Associated With Increased Risk of Recurrent Vascular Events in Older Minor Stroke or TIA Patients

Chan KL, Feng X, Ip B, Huang S, Ma SH, Fan FSY, Ip HL, Huang L, Mok VCT, Soo YOY, Leung TW, Leng X

Front Aging Neurosci. 2021 Apr 20;13:646961. doi: 10.3389/fnagi.2021.646961.

Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir

Ho Sing Lo, Kenrie Pui Yan Hui, Hei-Ming Lai, Xu He, Khadija Shahed Khan, Simranjeet Kaur, Junzhe Huang, Zhongqi Li, Anthony K. N. Chan, Hayley Hei-Yin Cheung, Ka-Chun Ng, John Chi Wang Ho, Yu Wai Chen, Bowen Ma, Peter Man-Hin Cheung, Donghyuk Shin, Kaidao Wang, Meng-Hsuan Lee, Barbara Selisko, Cecilia Eydoux, Jean-Claude Guillemot, Bruno Canard, Kuen-Phon Wu, Po-Huang Liang, Ivan Dikic, Zhong Zuo, Francis K. L. Chan, David S. C. Hui, Vincent C. T. Mok, Kam-Bo Wong, Chris Ka Pun Mok, Ho Ko, Wei Shen Aik, Michael Chi Wai Chan, and Wai-Lung Ng

ACS Cent Sci. 2021 April 15;doi.org/10.1021/acscentsci.0c01186.

Evolving ischemic stroke subtypes in 15 years: A hospital-based observational study

Ip B, Au L, Chan AYY, Fan F, Ip V, Ma SH, Ma K, Mok VCT, Lau A, Leng X, Leung H, Wong A, Abrigo J, Wong J, Yu S, Wong KS, Soo YOY, Leung TWH

Int J Stroke. 2021 Apr 7;17474930211005953. doi: 10.1177/17474930211005953.

Prevalence and predictors of mood disturbances in idiopathic REM sleep behaviour disorder

Chiu NKH, Ehgoetz Martens KA, Mok VCT, Lewis SJG, Matar E

J Sleep Res. . 2021 Apr;30(2):e13040. doi: 10.1111/jsr.13040.

A Data-Driven Approach to Transfer Function Analysis for Superior Discriminative Power: Optimized Assessment of Dynamic Cerebral Autoregulation

Liu J, Guo ZN, Simpson D, Zhang P, Liu C, Song JN, Leng X, Yang Y

IEEE J Biomed Health Inform. 2021;25:909-921.

Development of image-based risk scores for prediction of intracranial hemorrhage and ischemic stroke in patients taking antithrombotic therapy after ischemic stroke or transient ischemic attack: a pooled analysis of individual patient data from cohort studies

Best JG, Ambler G, Wilson D, Lee KJ, Lim JS, Shiozawa M, Koga M, Li L, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats-Sanchez L, Martínez-Domeño A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Ben Assayag E, Hallevi H, Molad J, Nishihara M, Tanaka J, Coutts SB, Polymeris A, Wagner B, Seiffge DJ, Lyrer P, Algra A, Kappelle LJ, Al-Shahi Salman R, Jäger HR, Lip GYH, Fischer U, El-Koussy M, Mas JL, Legrand L, Karayiannis C, Phan T, Gunkel S, Christ N, Abrigo J, Leung T, Chu W, Chappell F, Makin S, Hayden D, Williams DJ, Mess WH, Nederkoorn PJ, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Maaijwee N, Guevarra AC, Yatawara C, Mendyk AM, Delmaire C, Köhler S, van Oostenbrugge R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, Hendrikse J, Kelly PJ, Wardlaw J, Soo Y, Fluri F, Srikanth V, Calvet D, Jung S, Kwa VIH, Engelter ST, Peters N, Smith EE, Hara H, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Mok V, Veltkamp R, Ay H, Imaizumi T, Gomez-Anson B, Lau KK, Jouvent E, Rothwell PM, Toyoda K, Bae HJ, Marti-Fabregas J, Werring DJ; Microbleeds International Collaborative Network

Lancet Neurol. 2021 Apr;20(4):294-303. doi: 10.1016/S1474-4422(21)00024-7.

Current Status of Endovascular Treatment for Acute Large Vessel Occlusion in China: A Real-World Nationwide Registry

Jia B, Ren Z, Mokin M, Burgin WS, Bauer CT, Fiehler J, Mo D, Ma N, Gao F, Huo X, Luo G, Wang A, Pan Y, Song L, Sun X, Zhang X, Gui L, Song C, Peng Y, Wu J, Zhao S, Zhao J, Zhou Z, Li Y, Jing P, Yang L, Liu Y, Zhao Q, Liu Y, Peng X, Gao Q, Guo Z, Chen W, Li W, Cheng X, Xu Y, Zhang Y, Zhang G, Lu Y, Lu X, Wang D, Wang Y, Li H, Ling L, Peng G, Zhang J, Zhang K, Li S, Qi Z, Xu H, Tong X, Ma G, Liu R, Guo X, Deng Y, Leng X, Leung TW, Liebeskind DS, Wang Y, Wang Y, Miao Z; ANGEL-ACT Study Group

Stroke. 2021 Apr;52(4):1203-1212. doi: 10.1161/STROKEAHA.120.031869.

Recommendation to Use Wearable-Based mHealth in Closed-Loop Management of Acute Cardiovascular Disease Patients During the COVID-19 Pandemic

Ji N, Xiang T, Bonato P, Lovell NH, Ooi SY, Clifton DA, Akay M, Ding XR, Yan BP, Mok V, Fotiadis DI, Zhang YT

IEEE J Biomed Health Inform. 2021 Apr;25(4):903-908. doi: 10.1109/JBHI.2021.3059883. Epub 2021 Apr 6. PMID: 33596179.

Intracranial arterial stenosis in Caucasian versus Chinese patients with TIA and minor stroke: two contemporaneous cohorts and a systematic review

Leng XY, Hurford R, Feng XY, Chan KY, Wolters FJ, Li LX, Soo YOY, Wong LKS, Mok VCT, Leung TWH, Rothwell PM

J Neurol Neurosurg Psychiatry. 2021 Mar 30; doi: 10.1136/jnnp-2020-325630.

Teaching Video NeuroImages: A Triad of Tremor, Ataxia, and Cognitive Impairment

Au LWC, Ho K, Li JJX, Mok VCT

Neurology. 2021 Mar 30;96(13):e1802-e1803. doi: 10.1212/WNL.0000000000011288.

Endoscopy-assisted magnetic navigation of biohybrid soft microrobots with rapid endoluminal delivery and imaging

Wang B, Chan KF, Yuan K, Wang Q, Xia X, Yang L, Ko H, Wang YXJ, Sung JJY, Chiu PWY, Zhang L

Sci Robot. 2021 Mar 17;6(52):eabd2813. doi: 10.1126/scirobotics.abd2813. PMID: 34043547.

A retrospective comparison of cognitive performance in individuals with advanced Parkinson's Disease in Hong Kong and Canada

Kwan V, Shum D, Haffenden A, Yeates KO, Kwok A, Lau H, Poon WS, Chan D, Zhu XL, Chan D, Mok V, Chan A, Ma K, Yeung J, Lau C, Bezchlibnyk Y, Kiss Z, Tang V

Appl Neuropsychol Adult. 2021 Mar 15:1-9. doi: 10.1080/23279095.2021.1898396.

Intraluminal Thrombus and Outcomes of Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Treatment

Ding Y, Leng X, Nie X, Pan Y, Li J, Liu D, Yan H, Pu Y, Wei Y, Cai Y, Lu Q, Zhang Z, Duan W, Gu W, Hou X, Yang Z, Wen M, Ma N, Miao Z, Wang Y, Liu L, and on behalf of the RESCUE-RE Study Group

Stroke. 2021;52:1473–1477.

Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension

McCray BA, Diehl E, Sullivan JM, Aisenberg WH, Zaccor NW, Lau AR, Rich DJ, Goretzki B, Hellmich UA, Lloyd TE, Sumner CJ

Nat Commun. 2021 Mar 4;12(1):1444. doi: 10.1038/s41467-021-21699-y.

Dabigatran or Aspirin in East Asian Patients With Embolic Stroke of Undetermined Source: RE-SPECT ESUS Subgroup Analysis

Uchiyama S, Toyoda K, Lee BC, Liou CW, Wong LKS, Grauer C, Brueckmann M, Taniguchi A, Urano Y, Easton JD; RE-SPECT ESUS Investigators

Stroke. 2021 Mar;52(3):1069-1073. doi: 10.1161/STROKEAHA.120.031891.

High-Degree Middle Cerebral Artery Stenosis : Can Advanced 3D DSA-MRI Fusion Imaging Better Illustrate Plaques and Perforators?

Guan M, Lin J, Huang S, Leng X, Shi C, Qiao H, Wang X, Huang L

Clin Neuroradiol. 2021 Mar;31(1):51-59. doi: 10.1007/s00062-020-00927-w.

Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status

Liu D, Nie X, Pan Y, Yan H, Pu Y, Wei Y, Cai Y, Ding Y, Lu Q, Zhang Z, Gu W, Hou X, Yang Z, Wen M, Wang P, Ma G, Ma N, Miao Z, Leng X, Yan B, Davis SM, Wang Y, Liu L

J Am Heart Assoc. 2021 Feb;10(5):e019350. doi: 10.1161/JAHA.120.019350.

Identifying Biomarkers Associated with Venous Infarction in Acute/Subacute Cerebral Venous Thrombosis

Duan J, Leng X, Han Z, Cai Y, Wang C, Rajah G, Song H, Ding Y, Ji X

Aging Dis. 2021 Feb 1;12(1):93-101. doi: 10.14336/AD.2020.0405.

Effects of wearable ankle robotics for stair and over-ground training on sub-acute stroke: a randomized controlled trial

Yeung LF, Lau CCY, Lai CWK, Soo YOY, Chan ML, Tong RKY

J Neuroeng Rehabil. 2021 Jan 29;18(1):19. doi: 10.1186/s12984-021-00814-6.

Response by Lan et al to Letter Regarding Article, "Regional High Wall Shear Stress Associated With Stenosis Regression in Symptomatic Intracranial Atherosclerotic Disease"

Lan L, Liu H, Leung TW, Leng X

Stroke. 2021 Jan;52(2):e80-e81. doi: 10.1161/STROKEAHA.120.033341.

Modulation of Functional Connectivity and Low-Frequency Fluctuations After Brain-Computer Interface-Guided Robot Hand Training in Chronic Stroke: A 6-Month Follow-Up Study.

Lau CCY, Yuan K, Wong PCM, Chu WCW, Leung TW, Wong WW, Tong RKY

2021 Jan 20;14:611064. doi: 10.3389/fnhum.2020.611064. . Front Hum Neurosci

Correction: Electronic Cognitive Screen Technology for Screening Older Adults With Dementia and Mild Cognitive Impairment in a Community Setting: Development and Validation Study

Chan J, Wong A, Yiu B, Mok H, Lam P, Kwan P, Chan A, Mok VCT, Tsoi KKF, Kwok TCY

J Med Internet Res. 2021 Jan 19;23(1):e26724. doi: 10.2196/26724.

Frontotemporal dementia and COVID-19: Hypothesis generation and roadmap for future research

Ng KP, Chiew HJ, Hameed S, Ting SKS, Ng A, Soo SA, Wong BYX, Lim L, Yong ACW, Mok VCT, Rosa-Neto P, Dominguez J, Kim S, Hsiung GYR, Ikeda M, Miller BL, Gauthier S, Kandiah N

Alzheimers Dement (N Y). 2021 Jan 15;6(1):e12085. doi: 10.1002/trc2.12085.

Predictors of survival in frontotemporal lobar degeneration syndromes

El-Wahsh S, Finger EC, Piguet O, Mok V, Rohrer JD, Kiernan MC, Ahmed RM

J Neurol Neurosurg Psychiatry. 2021 Jan 13:jnnp-2020-324349. doi: 10.1136/jnnp-2020-324349.

An MRI-based strategy for differentiation of frontotemporal dementia and Alzheimer's disease

Yu Q, Mai Y, Ruan Y, Luo Y, Zhao L, Fang W, Cao Z, Li Y, Liao W, Xiao S, Mok VCT, Shi L, Liu J; National Alzheimer’s Coordinating Center, the Alzheimer’s Disease Neuroimaging Initiative; Frontotemporal Lobar Degeneration Neuroimaging Initiative

Alzheimers Res Ther. 2021 Jan 12;13(1):23. doi: 10.1186/s13195-020-00757-5.

Plaque Wall Distribution Pattern of the Atherosclerotic Middle Cerebral Artery associates with the Circle of Willis Completeness

Li J, Zheng L, Yang WJ, Sze-To CY, Leung TW, Chen XY

Front Neurol. 2021 Jan 11;11:599459. doi: 10.3389/fneur.2020.599459.

Pandemic of the aging society - sporadic cerebral small vessel disease

Lau AYL, Ip BYM, Ko H, Lam BYK, Shi L, Ma KKY, Au LWC, Soo YOY, Leung TWH, Wong A, Mok VCT

Chin Med J (Engl). 2021 Jan 5;134(2):143-150. doi: 10.1097/CM9.0000000000001320.

AD Resemblance Atrophy Index as a Diagnostic Biomarker for Alzheimer's Disease: A Retrospective Clinical and Biological Validation

Mai Y, Yu Q, Zhu F, Luo Y, Liao W, Zhao L, Xu C, Fang W, Ruan Y, Cao Z, Lei M, Au L, Mok VCT, Shi L, Liu J

J Alzheimers Dis. 2021;79(3):1023-1032. doi: 10.3233/JAD-201033.

High serum neurofilament levels among Chinese patients with aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders

Liu C, Zhao L, Fan P, Ko H, Au C, Ng A, Au L, Wong A, Kermode AG, Mok V, Yan Y, Qiu W, Lau AY

J Clin Neurosci. 2021 Jan;83:108-111. doi: 10.1016/j.jocn.2020.11.016.

Intracranial Atherosclerosis Coexisting With White Matter Hyperintensities May Predict Unfavorable Functional Outcome in Patients With Acute Cerebral Ischemia

Liu H, Pu Y, Wang Y, Zou X, Pan Y, Zhang C, Soo YOY, Leung TWH, Zhao X, Wong KSL, Wang Y, Liu L

Front Neurol. 2020 Dec 21;11:609607. doi: 10.3389/fneur.2020.609607. eCollection 2020.

Electronic Cognitive Screen Technology for Screening Older Adults With Dementia and Mild Cognitive Impairment in a Community Setting: Development and Validation Study

Chan JYC, Wong A, Yiu B, Mok H, Lam P, Kwan P, Chan A, Mok VCT, Tsoi KKF, Kwok TCY

J Med Internet Res. 2020 Dec 18;22(12):e17332. doi: 10.2196/17332.

Magnetic resonance imaging manifestations of cerebral small vessel disease: automated quantification and clinical application

Zhao L, Lee A, Fan YH, Mok VCT, Shi L

Chin Med J (Engl). 2020 Dec 16;134(2):151-160. doi: 10.1097/CM9.0000000000001299. PMID: 33443936; PMCID: PMC7817342.

High serum neurofilament levels among Chinese patients with aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders

Liu C, Zhao L, Fan P, Ko H, Au C, Ng A, Au L, Wong A, Kermode AG, Mok V, Yan Y, Qiu W, Lau AY

J Clin Neurosci. . 2020 Dec 11:S0967-5868(20)31639-8. doi: 10.1016/j.jocn.2020.11.016. Online ahead of print.

Quantitative Susceptibility Mapping of the Hippocampal Fimbria in Alzheimer's Disease

Au CKF, Abrigo J, Liu C, Liu W, Lee J, Au LWC, Chan Q, Chen S, Leung EYL, Ho CL, Ko H, Mok VCT, Chen W

J Magn Reson Imaging. 2020 Dec 9. doi: 10.1002/jmri.27464. Online ahead of print.PMID: 33295658.

Teaching Video Neuroimages: A triad of tremor, ataxia and cognitive impairment

Au LWC, Ho K, Li JJX, Mok VCT

Neurology. 2020 Dec 4:10.1212/WNL.0000000000011288. doi: 10.1212/WNL.0000000000011288. Online ahead of print.

Gastrodia-Uncaria water extract and tissue plasminogen activator for treating embolus-induced cerebral ischaemia: abridged secondary publication

Xian JW, Choi AYT, Leung WN, Li L, Lau CBS, Leung TWH, Chan CW

Hong Kong Med J. 2020 Dec;26 Suppl 7(6):45-47. PMID: 33229620.

Intracranial artery calcification to screen patients at high risk of recurrent stroke: abridged secondary publication

Wong KS, Chen XY, Leung TWH, Siu YW, Xiong L, Leng X

Hong Kong Med J. 2020 Dec;26 Suppl 7(6):42-44. PMID: 33229619.

Movement disorders associated with thiamine pyrophosphokinase deficiency: Intrafamilial variability in the phenotype

Au LWC, Lee HHC, Sheng B, Chan KY, Yau EKC, Mak CM, Chan AYW, Chan AYY, Lau CKY, Mok VCT, Lam CW

Clin Neurol Neurosurg. 2020 Dec;199:106258. doi: 10.1016/j.clineuro.2020.106258. Epub 2020 Sep 30.PMID: 33031988.

Stochastic stimulation of the motor cortex for treating parkinsonian symptoms: abridged secondary publication

Yung WH, Mok VCT, Ke Y.

Hong Kong Med J. . 2020 Dec;26 Suppl 7(6):23-25.

Plaque morphology in acute symptomatic intracranial atheroscleroticdisease

Leung TW, Wang L, Zou X, Soo Y, Pu Y, Ip HL, Chan A, Au LWC, Fan F, Ma SH, Ip B, Ma K, Lau AY, Leung H, Hui KF, Li R, Li SH, Fu M, Fong WC, Liu J, Mok V, Wong KSL, Miao Z, Ma N, Yu SCH, Leng X

J Neurol Neurosurg Psychiatry. 2020 Nov 25:jnnp-2020- 325027. doi: 10.1136/jnnp-2020-325027.

Effect of microcirculatory resistance on coronary blood flow and instantaneous wave-free ratio: A computational study

Liu H, Ou S, Liu P, Xu Y, Gong Y, Xia L, Leng X, Leung TWH, Shi L, Zheng D

Comput Methods Programs Biomed. 2020 Nov;196:105632. doi: 10.1016/j.cmpb.2020.105632. Epub 2020 Jun 25.

Residual Injurious Symptoms and Its Association With Neurodegenerative Outcomes in Idiopathic Rapid Eye Movement Sleep Behavior Disorder: A Retrospective, Longitudinal Follow-up Study

Wang J, Liu Y, Chau SWH, Zhang J, Tsang J, Yu MWM, Chan NY, Chan JWY, Li SX, Huang B, Feng H, Mok V, Wing YK

Mov Disord. 2020 Nov;35(11):2077-2085. doi: 10.1002/mds.28210. Epub 2020 Aug 3.

Fostering gerontology students' competence in Interprofessional collaborative practice

Chau JPC, Lo SHS, Lee VWY, Yiu WM, Chiang HCY, Thompson DR, Lau AYL

BMC Med Educ. 2020 Oct 27;20(1):388. doi: 10.1186/s12909-020-02273-4.

Hong Kong College of Physicians Position Statement and Recommendations on the 2017 American College of Cardiology/American Heart Association and 2018 European Society ofCardiology/European Society of Hypertension Guidelines for Management of Arterial Hypertension

Chan KK, Szeto CC, Lum CCM, Ng PW, Kong APS, Lau KP, Leung JYY, Lui SL, Mo KL, Mok FCK, Mok VCT, Yan BPY, Li PKT

Hong Kong Med J. 2020 Oct;26(5):432-437. doi: 10.12809/hkmj198330.PMID: 33089788.

Prolonged visual fixation as a surrogate marker of cholinergic deficit in Parkinson's disease: A 2-year follow-up study

Wong OW, Chan A, Wong A, Lau CK, Yeung JH, Mok V, Chan S

Parkinsonism Relat Disord. 2020 Dec;81:60-66. doi: 10.1016/j.parkreldis.2020.10.019. Epub 2020 Oct 11.

Intracranial Arterial Calcification Relates to Long-Term Risk of Recurrent Stroke and Post-stroke Mortality

Wu X, Bos D, Ren L, Leung TW, Chu WC, Wong LKS, Abrigo J, Chen XY

Front Neurol. 2020 Oct 9;11:559158. doi: 10.3389/fneur.2020.559158. PMID: 33162927; PMCID: PMC7581678.

Rest-Activity Pattern Alterations in Idiopathic REM Sleep Behavior Disorder

Feng H, Chen L, Liu Y, Chen X, Wang J, Yu MWM, Huang B, Li SX, Chau SWH, Chan JWY, Chen J, Mok VCT, Wing YK, Zhang J

Ann Neurol. 2020 Oct;88(4):817-829. doi: 10.1002/ana.25853. Epub 2020 Aug 18.

Regional High Wall Shear Stress Associated With Stenosis Regression in Symptomatic Intracranial Atherosclerotic Disease

Lan L, Liu H, Ip V, Soo Y, Abrigo J, Fan F, Ma SH, Ma K, Ip B, Liu J, Fan Y, Zeng J, Mok V, Wong L, Liebeskind D, Leung T, Leng X

Stroke. 2020 Oct;51(10):3064-3073. doi: 10.1161/STROKEAHA.120.030615. Epub 2020 Sep 4.

Effects of a multidisciplinary team-led school-based human papillomavirus vaccination health-promotion programme on improving vaccine acceptance and uptake among female adolescents: A cluster randomized controlled trial

Chau JPC, Lo SHS, Choi KC, Lee VWY, Lui GCY, Chan KM, Lau AYL

Medicine (Baltimore). 2020 Sep 11;99(37):e22072. doi: 10.1097/MD.0000000000022072.

Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain

Lei Zhao, Zhongqi Li, Joaquim S L Vong, Xinyi Chen, Hei-Ming Lai, Leo Y C Yan, Junzhe Huang, Samuel K H Sy, Xiaoyu Tian, Yu Huang, Ho Yin Edwin Chan, Hon-Cheong So, Wai-Lung Ng, Yamei Tang, Wei-Jye Lin, Vincent C T Mok, Ho Ko

Nat Commun. 2020 Sep 4;11(1):4413. doi:10.1038/s41467-020-18249-3.

Nurse Led Smartphone Electrographic Monitoring for Atrial Fibrillation after Ischemic Stroke: SPOT-AF

Yan B, Tu H, Lam C, Swift C, Ma SH, Mok VCT, Sui Y, Sharpe D, Ghia D, Jannes J, Davis S, Liu X, Freedman B

J Stroke. 2020 Sep;22(3):387-395. doi: 10.5853/jos.2020.00689. Epub 2020 Sep 29.PMID: 33053954.

Advanced MRI features in relapsing multiple sclerosis patients with and without CSF oligoclonal IgG bands

Zhao L, Abrigo J, Chen Q, Au C, Ng A, Fan P, Mok V, Qiu W, Kermode AG, Lau AY

Sci Rep. 2020 Aug 13;10(1):13703. doi: 10.1038/s41598-020-70693-9. PMID: 32792656; PMCID: PMC7426866.

Tackling challenges in care of Alzheimer’s disease and other dementias amid the COVID-19 pandemic, now and in the future

Mok VCT, Pendlebury S, Wong A, Alladi S, Au L, Bath P, GJ, Chen C, Cordonnier C, Dichgans M, Dominguez J, Gorelick PB, Kim SY, Kwok T, Greenberg SM, Jia J, Kalaria R, Kivipelto M, Naegandran K, Lam LCW, Lam BYK, Lee ATC, Markus HS, O’Brien J, Pai MC, Pantoni L, Sachdev P, Skoog I, Smith EE, Srikanth V, Suh GH, Wardlaw J, Ko H, Black SE, Scheltens P

Alzheimer's & Dementia. 2020 Aug 12;doi:10.1002/alz.12143

Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

Zhou X, Chen Y, Ip FCF, Lai NCH, Li YYT, Jiang Y, Zhong H, Chen Y, Zhang Y, Ma S, Lo RMN, Cheung K, Tong EPS, Ko H, Shoai M, Mok KY, Hardy J, Mok VCT, Kwok TCY, Fu AKY, Ip NY

Alzheimers Dement (Amst). 2020 Aug 5;12(1):e12074. doi: 10.1002/dad2.12074. eCollection 2020.PMID: 32775599.

Lipid-Bilayer-Supported 3D Printing of Human Cerebral Cortex Cells Reveals Developmental Interactions

Zhou L, Wolfes AC, Li Y, Chan DCW, Ko H, Szele FG, Bayley H

Adv Mater. 2020 Aug;32(31):e2002183. doi: 10.1002/adma.202002183. Epub 2020 Jun 14. PMID: 32537827.

Regression of Plaque Enhancement Within Symptomatic Middle Cerebral Artery Atherosclerosis: A High-Resolution MRI Study

Yang WJ, Abrigo J, Soo YO, Wong S, Wong KS, Leung TW, Chu WC, Chen XY.

Front Neurol. 2020 Jul 28;11:755. doi: 10.3389/fneur.2020.00755

High White Matter Hyperintensity Burden in Strategic White Matter Tracts Relates to Worse Global Cognitive Performance in Community-Dwelling Individuals

BIESBROEK JM, LAM BYK, ZHAO L, TANG Y, WANG Z, ABRIGO J, CHU WWC, WONG A, SHI L, KUIJF HJ, BIESSELS GJ, MOK VCT

J Neurol Sci. 2020 Jul 15;414:116835. doi: 10.1016/j.jns.2020.116835. Epub 2020 Apr 13.

Dataset on blood flow and instantaneous wave-free ratio in normal and stenosed coronary arteries

Liu H, Ou S, Liu P, Xu Y, Gong Y, Xia L, Leng X, Leung TWH, Shi L, Zheng D

Data Brief. 2020 Jul 11;32:106011. doi: 10.1016/j.dib.2020.106011. eCollection 2020 Oct.

State-of-the-art Computational Models of Circle of Willis with Physiological Applications: A Review

Liu H, Wang D, Leng X, Zheng D, Chen F, Wong LKS, Shi L, Leung TWH

IEEE Access. 2020 Jul; 8:156261-156273. doi: 10.1109/ACCESS.2020.3007737.

Impaired cognition is related to microstructural integrity in relapsing remitting multiple sclerosis

Zhao L, Ng A, Chen Q, Lam B, Abrigo J, Au C, Mok VCT, Wong A, Lau AY

Ann Clin Transl Neurol. 2020 Jul;7(7):1193-1203. doi: 10.1002/acn3.51100. Epub 2020 Jun 9. PMID: 32519512; PMCID: PMC7359116.

Assessing the Predictive Validity of Simple Dementia Risk Models in Harmonized Stroke Cohorts

Tang EYH, Price CI, Robinson L, Exley C, Desmond DW, Köhler S, Staals J, Yin Ka Lam B, Wong A, Mok V, Bordet R, Bordet AM, Dondaine T, Lo JW, Sachdev PS, Stephan BCM; STROKOG Collaboration

Stroke. 2020 Jul;51(7):2095-2102. doi: 10.1161/STROKEAHA.120.027473. Epub 2020 Jun 17.

Impaired Cognition Is Related to Microstructural Integrity in Relapsing Remitting Multiple Sclerosis

ZHAO L, NG A, CHEN Q, LAM B, ABRIGO J, AU C, MOK VCT, WONG A, LAU AY

Ann Clin Transl Neurol. 2020 Jun 9. doi: 10.1002/acn3.51100. Online ahead of print.

Risk of COVID-19 infection in MS and neuromyelitis optica spectrum disorders

Fan M, Qiu W, Bu B, Xu Y, Yang H, Huang D, Lau AY, Guo J, Zhang MN, Zhang X, Yang CS, Chen J, Zheng P, Liu Q, Zhang C, Shi FD

Neurol Neuroimmunol Neuroinflamm. 2020 Jun 4;7(5):e787. doi: 10.1212/NXI.0000000000000787. PMID: 32503092; PMCID: PMC7286663.

Decreased Visible Deep Medullary Veins Is a Novel Imaging Marker for Cerebral Small Vessel Disease

CHEN X, WEI L, WANG J, SHAN Y, CAI W, MEN X, LIU S, KANG Z, LU Z, MOK VCT, WU A

Neurol Sci. 2020 Jun;41(6):1497-1506. doi: 10.1007/s10072-019-04203-9. Epub 2020 Jan 18.

Risk of COVID-19 infection in MS and neuromyelitis optica spectrum disorders

Fan M, Qiu W, Bu B, Xu Y, Yang H, Huang D, Lau AY, Guo J, Zhang MN, Zhang X, Yang CS, Chen J, Zheng P, Liu Q, Zhang C, Shi FD

Neurol Neuroimmunol Neuroinflamm. 2020 Jun 4;7(5):e787. doi: 10.1212/NXI.0000000000000787.

Herb-Drug Interaction of Gastrodiae Rhizoma on Carbamazepine: A Pharmacokinetic Study in Rate

YIP KL, ZHOU X, CHOOK P, LEUNG PC, SCHACHTER S, MOK VCT, LEUNG TWH, KOON CM, LEUNG H

Epilepsy Res. 2020 May 31; 165. doi: 10.1016/j.eplepsyres.2020.106376

Indoor incense burning impacts cognitive functions and brain functional connectivity in community older adults

Wong A, Lou W, Ho KF, Yiu BK, Lin S, Chu WC, Abrigo J, Lee D, Lam BY, Au LW, Soo YO, Lau AY, Kwok TC, Leung TW, Lam LC, Ko H, Mok VCT

Sci Rep. 2020 Apr 27;10(1):7090. doi: 10.1038/s41598-020-63568-6.

Translesional Pressure Gradient Alters Relationship Between Blood Pressure and Recurrent Stroke in Intracranial Stenosis

FENG X, CHAN KL, LAN L, ABRIGO J, IP VHL, SOO YOY, LEUNG TW, LENG X

Stroke. 2020 Jun;51(6):1862-1864. doi: 10.1161/STROKEAHA.119.028616. Epub 2020 Apr 21.

Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study

FOO JN, CHEW EGY, CHUNG SJ, PENG R, BLAUWENDRAAT C, NALLS MA, MOK KY, SATAKE W, TODA T, CHAO Y, TAN LCS, TANDIONO M, LIAN MM, NG EY, PRAKASH KM, AU WL, MEAH WY, MOK SQ, ANNUAR AA, CHAN AYY, CHEN L, CHEN Y, JEON BS, JIANG L, LIM JL, LIN JJ, LIU C, MAO C, MOK V, PEI Z, SHANG HF, SHI CH, SONG K, TAN AH, WU YR, XU YM, XU R, YAN Y, YANG J, ZHANG B, KOH WP, LIM SY, KHOR CC, LIU J, TAN EK

JAMA Neurol. 2020 Apr 20;e200428. doi: 10.1001/jamaneurol.2020.0428.

Hemodynamic Significance of Middle Cerebral Artery Stenosis Associated With the Severity of Ipsilateral White Matter Changes

FANG H, LENG X, PU Y, ZOU X, PAN Y, SONG B, SOO YOY, LEUNG TWH, WANG C, ZHAO X, WANG Y, WANG Y, WONG KS, LIU L, XU Y, CICAS STUDY GROUP

Front Neurol. 2020 Apr 15;11:214. doi: 10.3389/fneur.2020.00214. eCollection 2020.

Prevalence and Predictors of Mood Disturbances in Idiopathic REM Sleep Behaviour Disorder

CHIU NKH, EHGOETZ MARTENS KA, MOK VCT, LEWIS SJG, MATAR E

J Sleep Res. 2020 Apr 7;e13040. doi: 10.1111/jsr.13040. Online ahead of print.

Stroke Outcome Prediction by Blood Pressure Variability, Heart Rate Variability, and Baroreflex Sensitivity

TANG S, XIONG L, FAN Y, MOK VCT, WONG KS, LEUNG TW

Stroke. 2020 Apr;51(4):1317-1320. doi: 10.1161/STROKEAHA.119.027981. Epub 2020 Jan 22.

Association Between Advanced Interatrial Block and Small Vessel Diseases in the Brain

WANG Z, QIN H, CHEN G, MOK VCT, DAI Y, CAI Y, CHENG X, QIAN Y, CHU M, LU X

Quant Imaging Med Surg. 2020 Mar;10(3):585-591. doi: 10.21037/qims.2020.02.02.

UK Consensus on Pre-Clinical Vascular Cognitive Impairment Functional Outcomes Assessment: Questionnaire and Workshop Proceedings

MCFALL A, HIETAMIES TM, BERNARD A, AIMABLE M, ALLAN SM, BATH PM, BREZZO G, CARARE RO, CARSWELL HV, CLARKSON AN, CURRIE G, FARR TD, FOWLER JH, GOOD M, HAINSWORTH AH, HALL C, HORSBURGH K, KALARIA R, KEHOE P, LAWRENCE C, MACLEOD M, MCCOLL BW, MCNEILLY A, MILLER AA, MINERS S, MOK V, O'SULLIVAN M, PLATT B, SENA ES, SHARP M, STRANGWARD P, SZYMKOWIAK S, TOUYZ RM, TRUEMAN RC, WHITE C, MCCABE C, WORK LM, QUINN TJ

J Cereb Blood Flow Metab. 2020 Mar 9;271678X20910552. doi: 10.1177/0271678X20910552. Online ahead of print.

Contra-Directional Expression of Plasma Superoxide Dismutase With Lipoprotein Cholesterol and High-Sensitivity C-reactive Protein as Important Markers of Parkinson's Disease Severity

YANG W, CHANG Z, QUE R, WENG G, DENG B, WANG T, HUANG Z, XIE F, WEI X, YANG Q, LI M, MA K, ZHOU F, TANG B, MOK VCT, ZHU S, WANG Q.

Front Aging Neurosci. 2020 Mar 6;12:53. doi: 10.3389/fnagi.2020.00053. eCollection 2020.

The Role of Cerebral Microbleeds in the Incidence of Post-Stroke Dementia

YATAWARA C, GUEVARRA AC, NG KP, CHANDER R, LAM BYK, WONG A, MOK V, KANDIAH N

J Neurol Sci. 2020 May 15;412:116736. doi: 10.1016/j.jns.2020.116736. Epub 2020 Feb 15.

Pathophysiology of Vascular Cognitive Impairment (II): Amyloid Contribution in Vascular Cognitive Impairment

KO H, LAM BYK, MOK VCT

Stroke Revisited: Vascular Cognitive Impairment.. 2020;87-97. ISBN 978-981-10-1433-8.

Is the future of symptomatic intracranial atherosclerotic stenosis management promising?

Liu D, Liu J, Cai Y, Wong KSL, Liu L

J Neurol Neurosurg Psychiatry. 2020 Feb;91(2):122- 124. doi: 10.1136/jnnp-2019-321564.

Screening for Chronic Conditions With Reproductive Factors Using a Machine Learning Based Approach

TIAN S, DONG W, CHAN KL, LENG X, BEDFORD LE, LIU J

Sci Rep. 2020 Feb 18;10(1):2848. doi: 10.1038/s41598-020-59825-3.

Protocols of Non-Invasive Brain Stimulation for Neuroplasticity Induction

HE W, FONG PY, LEUNG TWH, HUANG YZ

Neurosci Lett. 2020 Feb 6;719:133437. doi: 10.1016/j.neulet.2018.02.045. Epub 2018 Feb 21.

Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial

Liu X, Dai Q, Ye R,… Leung T …, Nogueira RG

Lancet Neurol. 2020 Feb;19(2):115-122. doi: 10.1016/S1474-4422(19)30395-3

Pneumocystis Pneumonia in a Patient Treated With Alemtuzumab for Relapsing Multiple Sclerosis

LAU AY, LUI GCY, CHAN KP, AU C, MOK VCT, ZIEMSSEN T

Mult Scler Relat Disord. 2020 Feb;38:101503. doi: 10.1016/j.msard.2019.101503. Epub 2019 Nov 6.

Characteristics of Wall Shear Stress and Pressure of Intracranial Atherosclerosis Analyzed by a Computational Fluid Dynamics Model: A Pilot Study

CHEN Z, QIN H, LIU J, WU B, CHENG Z, JIANG Y, LIU L, JING L, LENG X, JING J, WANG Y, WANG Y

Front Neurol. 2020 Jan 17;10:1372. doi: 10.3389/fneur.2019.01372. eCollection 2019.

Treatment patterns of patients with multiple sclerosis in Guangzhou, China

Li R, Wang J, Li J, Wang Y, Wu H, Fan P, Lau AY, Kermode A, Qiu W

Neurology Asia. 2020; 25(2):173-182. (IF 0.240)

Dementia in China: Epidemiology, Clinical Management, and Research Advances

JIA L, QUAN M, FU Y,  ZHAO T, LI Y, WEI C, TANG Y, QIN Q, WANG F, QIAO Y, SHI S, WANG YJ, DU Y, ZHANG J, ZHANG J, LUO B, QU Q, ZHOU C, GAUTHIER S, JIA J, ZHOU A, ZUO X, CHU C, YU Y, CHANG H, LI D, GUO D, XING Y, HUANG X, QIU Q, XU H, YAN X, CHEN S, YANG J, LYU J, JIA Z, HUANG Y, JIA J, PENG D, JI Y, GUO Q, CAO Y, SUN L, LI Y, LYU P, GANG B, ZHANG N, TAN L, TANG H, LI H, LIAO Z, LIU J, LU Y, XU J, ZHANG K, SHI X, JI X, LI X, GUO Y, BI J, MOK VCT, KAN M, LI F, ZHOU W, CHU L, YANG S, YANG H, YOU Y

Lancet Neurol. 2020 Jan;19(1):81-92. doi: 10.1016/S1474-4422(19)30290-X. Epub 2019 Sep 4.

Topological Reorganization of the Default Mode Network in Patients With Poststroke Depressive Symptoms: A Resting-State fMRI Study

LIANG Y, YAO YC, ZHAO L, SHI L, CHEN YK, MOK VC, UNGVARI GS, CHU WC, TANG WK

J Affect Disord. 2020 Jan 1;260:557-568. doi: 10.1016/j.jad.2019.09.051. Epub 2019 Sep 11.

Sustaining Cerebral Perfusion in Intracranial Atherosclerotic Stenosis: The Roles of Antegrade Residual Flow and Leptomeningeal Collateral Flow

LAN L, Leng X, IP V, Soo Y, ABRIGO J, LIU H, FAN F, MA SH, MA K, IP BY, CHAN KL, MOK VC, LIEBESKIND DS, WONG KS, LEUNG TW

J Cereb Blood Flow Metab. 2020 Jan;40(1):126-134. doi: 10.1177/0271678X18805209. Epub 2018 Oct 23.

Development of a Delayed Cerebral Infarction Load Scoring System (DCI Score)

WONG GKC, NUNG RCH, SITT JCM, MOK VCT, WONG A, POON WS, WANG D, ABRIGO J, SIU DYW

Acta Neurochir Suppl. 2020;127:145-148. doi: 10.1007/978-3-030-04615-6_21.

Autoimmune Glial Fibillary Acidic Protein Astrocytopathy Associated Meningoencephalomyelitis and Bilateral Sensorineuronal Deafness

IP B, LAM C, IP V, CHAN A, MOK V, AU E, CHAN E, LAU A

Mult Scler Relat Disord. 2020 May;40:101922. doi: 10.1016/j.msard.2019.101922. Epub 2019 Dec 31.

The antiepileptic effect of Gastrodiae Rhizoma through modulating overexpression of mTOR and attenuating astrogliosis in pilocarpine mice model

Yip KL, Koon CM, Chen ZY, Chook P, Leung PC, Schachter S, Leung WH, Mok CT, Leung H

Epilepsia Open. 2019 Dec 13;5(1):50-60. doi: 10.1002/epi4.12372. PMID: 32140643; PMCID: PMC7049815.

A Targeted Gene Panel That Covers Coding, Non-coding and Short Tandem Repeat Regions Improves the Diagnosis of Patients With Neurodegenerative Diseases

YU AC, YIM AK, CHAN AY, YUEN LYP, AU WC, CHENG THT, LIN X, LI JW, CHAN LWL, MOK VCT, CHAN TF, CHAN HYE

Front Neurosci. 2019 Dec 11;13:1324. doi: 10.3389/fnins.2019.01324. eCollection 2019.

Profile of and risk factors for poststroke cognitive impairment in diverse ethnoregional groups

Lo JW, Crawford JD, Desmond DW, Godefroy O, Jokinen H, Mahinrad S, Bae HJ, Lim JS, Köhler S, Douven E, Staals J, Chen C, Xu X, Chong EJ, Akinyemi RO, Kalaria RN, Ogunniyi A, Barbay M, Roussel M, Lee BC, Srikanth VK, Moran C, Kandiah N, Chander RJ, Sabayan B, Jukema JW, Melkas S, Erkinjuntti T, Brodaty H, Bordet R, Bombois S, Hénon H, Lipnicki DM, Kochan NA, Sachdev PS; Stroke and Cognition (STROKOG) Collaboration

Neurology. 2019 Dec 10;93(24):e2257-e2271. doi: 10.1212/WNL.0000000000008612. Epub 2019 Nov 11. PMID: 31712368; PMCID: PMC6937495.

Effects of functional tasks exercise on cognitive functions of older adults with mild cognitive impairment: a randomized controlled pilot trial

Law LLF, Mok VCT, Yau MMK

Alzheimers Res Ther. 2019 Dec 4;11(1):98. doi: 10.1186/s13195-019-0548-2. PMID: 31801630; PMCID: PMC6894271.

Response by Feng Et Al to Letter Regarding Article, "Stroke Mechanisms in Symptomatic Intracranial Atherosclerotic Disease: Classification and Clinical Implications"

FENG X, LEUNG TW, LENG X

Stroke. 2019 Dec;50(12):e437. doi: 10.1161/STROKEAHA.119.027738. Epub 2019 Nov 13.

Neuroimaging in Vascular Parkinsonism

MA KKY, LIN S, MOK VCT

Curr Neurol Neurosci Rep. 2019 Nov 26;19(12):102. doi: 10.1007/s11910-019-1019-7.

Mapping the Patterns of Cortical Thickness in Single- And Multiple-Domain Amnestic Mild Cognitive Impairment Patients: A Pilot Study

SUN P, LOU W, LIU J, SHI L, LI K, WANG D, MOK VC, LIANG P

Aging (Albany NY). 2019 Nov 22;11(22):10000-10015. doi: 10.18632/aging.102362. Epub 2019 Nov 22.

Prevalence and Clinical Correlates of Poststroke Behavioral Dysexecutive Syndrome

TANG WK, LAU CG, LIANG Y, WANG L, MOK V, SOO OYY, LEUNG WHT, UNGVARI GS, UCHIYAMA S, KIM JS

J Am Heart Assoc. 2019 Nov 19;8(22):e013448. doi: 10.1161/JAHA.119.013448. Epub 2019 Nov 7.

Cerebral Small Vessel Disease Burden Is Associated With Accelerated Poststroke Cognitive Decline: A 1-Year Follow-Up Study

LIANG Y, CHEN YK, LIU YL, MOK VCT, UNGVARI GS, CHU WCW, SEO SW, TANG WK

J Geriatr Psychiatry Neurol. 2019 Nov;32(6):336-343. doi: 10.1177/0891988719862630.

Automated Brain MRI Volumetry Differentiates Early Stages of Alzheimer's Disease From Normal Aging

ZHAO W, LUO Y, ZHAO L, MOK V, SU L, YIN C, SUN Y, LU J, SHI L, HAN Y

J Geriatr Psychiatry Neurol. 2019 Nov;32(6):354-364. doi: 10.1177/0891988719862637.

Peak width of skeletonized mean diffusivity and its association with age-related cognitive alterations and vascular risk factors

Lam BYK, Leung KT, Yiu B, Zhao L, Biesbroek JM, Au L, Tang Y, Wang K, Fan Y, Fu JH, Xu Q, Song H, Tian X, Chu WCW, Abrigo J, Shi L, Ko H, Lau A, Duering M, Wong A, Mok VCT

Alzheimer's & dementia (Amsterdam, Netherlands). 2019 Oct 25;11:721-729. doi: 10.1016/j.dadm.2019.09.003. PMID: 31700990; PMCID: PMC6829102.

Stroke mechanisms in symptomatic intracranial atherosclerosis disease

Feng X, Chan KL, Lan L, Abrigo J, Liu J, Fang H, Xu Y, Soo Y, Leng X, Leung TW (corresponding author)

Stroke. 2019 Oct;50(10):2692-2699. doi: 10.1161/STROKEAHA.119.025732.

Neural evidence for long-term marriage shaping the functional brain network organization between couples

Shi L, Lou W, Wong A, Zhang F, Abrigo J, Chu WC, Kwok TC, Wong KK, Abbott D, Wang D, Mok VC.

Neuroimage. 2019 Oct 1;199:87-92. doi: 10.1016/j.neuroimage.2019.05.058. Epub 2019 May 23.

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study.

NeuroVISION Investigators

Lancet. . 2019 Sep 21;394(10203):1022-1029. doi: 10.1016/S0140-6736(19)31795-7. Epub 2019 Aug 15. PMID: 31422895.

Frequency and longitudinal clinical outcomes of Alzheimer's AT(N) biomarker profiles: A longitudinal study

Yu JT, Li JQ, Suckling J, Feng L, Pan A, Wang YJ, Song B, Zhu SL, Li DH, Wang HF, Tan CC, Dong Q, Tan L, Mok V, Aisen PS, Weiner MM; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2019 Sep;15(9):1208-1217. doi: 10.1016/j.jalz.2019.05.006. Epub 2019 Aug 6.

Overview of Systematic Reviews with Meta-Analyses on Chinese Herbal Medicine in Stroke Management

HUNG CY, CHUNG VC, WU XY, HO RST, TANG EC, WU JCY, LAU AYL Adv

Integr. Med. . 2019 Sep;6(3):126-138. doi: 10.1016/j.aimed.2018.11.002

Can transcranial Doppler ultrasound be used for screening cerebral small vessel diseases in the community?

Kang D, Wong A, Fu J, Qun X, Liu W, Wang Z, Lin S, Kwan P, Lo E, Au LWC, Ko H, Lau AYL, Leung TWH, Abrigo J, Chu WCW, Mok VCT, Lam BYK.

J Neurol Sci. 2019 Aug 29;406:116439. doi: 10.1016/j.jns.2019.116439. [Epub ahead of print]

Risk estimation before progression to mild cognitive impairment and Alzheimer's disease: an AD resemblance atrophy index.

Zhao L, Luo Y, Lew D, Liu W, Au L, Mok V, Shi L; Alzheimer Disease Neuroimaging Initiative.

Aging (Albany NY). 2019 Aug 29;11(16):6217-6236. doi: 10.18632/aging.102184. Epub 2019 Aug 29.

Physical activities attenuate the negative cognitive impact from white matter hyperintensities in stroke and TIA patients with low education

Wong A, Yiu S, Lam BYK, Leung KT, Shi L, Lo E, Abrigo J, Au LW, Lau A, Mok V.

Int J Geriatr Psychiatry. 2019 Aug 13. doi: 10.1002/gps.5194. [Epub ahead of print]

Souvenaid in the management of mild cognitive impairment: an expert consensus opinion

Cummings J, Passmore P, McGuinness B, Mok V, Chen C, Engelborghs S, Woodward M, Manzano S, Garcia-Ribas G, Cappa S, Bertolucci P, Chu LW.

Alzheimers Res Ther. 2019 Aug 17;11(1):73. doi: 10.1186/s13195-019-0528-6. Review.

Teaching NeuroImages: X-linked adrenoleukodystrophy: Spinocerebellar variant

Au LWC, Chan AYY, Mok VCT.

Neurology. 2019 Aug 13;93(7):e731-e732. doi: 10.1212/WNL.0000000000007958. No abstract available. 

Autonomic Dysfunction in Neurological Disorders

XIONG L, LEUNG TWH

Aging (Albany NY). 2019 Apr 9;11(7):1903-1904. doi: 10.18632/aging.101896. . https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503877/

Neutralising Antibodies to Interferon-Beta Therapy in Relapsing Multiple Sclerosis: A Pilot Study

LAU AYL, CHAN E, LAU KK, MOK V, SIU DYW, LEE R

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):22-25. https://pubmed.ncbi.nlm.nih.gov/31416982/

Effects of Collateral Circulation on Haemodynamic Flow Status in Intracranial Artery Stenosis Depicted by Computational Fluid Dynamics

LEUNG TWH, FAN SY, IP HL, LAU AYL, SIU DYW, DAI EYL, WONG LKS, LIEBESKIND DS

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):18-21

Autonomic Dysfunction as Measured by Ewing Battery Test to Predict Poor Outcome After Acute Ischaemic Stroke

XIONG L, TIAN G, LEUNG HW, CHEN XY, LIN WH, LEUNG TWH, SOO YO, SIU DYW, WONG LKS

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):9-11.

Risk of Intracerebral Haemorrhage in Patients With Cerebral Microbleeds Taking Warfarin for Atrial Fibrillation: A Prospective Study

SOO YO, ABRIGO J, CHU W, LEUNG KT, FONG WC, LI SH, LI R, NG PW, WONG KK, WONG LKS, LEUNG TWH

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):6-8.

Plasma Lipoprotein-associated Phospholipase A2 and Superoxide Dismutase Are Independent Predicators of Cognitive Impairment in Cerebral Small Vessel Disease Patients: Diagnosis and Assessment

ZHU S, WEI X, YANG X, HUANG Z, CHANG Z, XIE F, YANG Q, DING C, XIANG W, YANG H, XIA Y, FENG ZP, SUN HS, YENARI MA, SHI L, MOK VC, WANG Q

Aging Dis. 2019 Aug 1;10(4):834-846. doi: 10.14336/AD.2019.0304. eCollection 2019 Aug.

Non-coding variability at the APOE locus contributes to the Alzheimer's risk

Zhou X, Chen Y, Mok KY, Kwok TCY, Mok VCT, Guo Q, Ip FC, Chen Y, Mullapudi N; Alzheimer’s Disease Neuroimaging Initiative, Giusti-Rodríguez P, Sullivan PF, Hardy J, Fu AKY, Li Y, Ip NY.

Nat Commun. 2019 Jul 25;10(1):3310. doi: 10.1038/s41467-019-10945-z.

An injectable implant to stimulate the sphenopalatine ganglion for treatment of acute ischaemic stroke up to 24 h from onset (ImpACT-24B): an international, randomised, double-blind, sham-controlled, pivotal trial

Bornstein NM, Saver JL, Diener HC … Leung TWH … Devlin T on behalf of the ImpACT-24B investigators

Lancet. 2019 Jul 20;394(10194):219-229. doi: 10.1016/S0140-6736(19)31192-4. Epub 2019 May 24.

Comparison of Feature Selection Methods and Machine Learning Classifiers for Radiomics Analysis in Glioma Grading

SUN P, WANG D, MOK VC, SHI L

IEEE Access. Vol. 7, pp. 102010-102020, 2019, doi: 10.1109/ACCESS.2019.2928975.

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

Wilson D, Ambler G, Lee KJ, Lim JS, Shiozawa M, Koga M, Li L, Lovelock C, Chabriat H, Hennerici M, Wong YK, Mak HKF, Prats-Sánchez L, Martínez-Domeño A, Inamura S, Yoshifuji K, Arsava EM, Horstmann S, Purrucker J, Lam BYK, Wong A, Kim YD, Song TJ, Schrooten M, Lemmens R, Eppinger S, Gattringer T, Uysal E, Tanriverdi Z, Bornstein NM, Assayag EB, Hallevi H, Tanaka J, Hara H, Coutts SB, Hert L, Polymeris A, Seiffge DJ, Lyrer P, Algra A, Kappelle J, Al-Shahi Salman R, Jäger HR, Lip GYH, Mattle HP, Panos LD, Mas JL, Legrand L, Karayiannis C, Phan T, Gunkel S, Christ N, Abrigo J, Leung T, Chu W, Chappell F, Makin S, Hayden D, Williams DJ, Kooi ME, van Dam-Nolen DHK, Barbato C, Browning S, Wiegertjes K, Tuladhar AM, Maaijwee N, Guevarra C, Yatawara C, Mendyk AM, Delmaire C, Köhler S, van Oostenbrugge R, Zhou Y, Xu C, Hilal S, Gyanwali B, Chen C, Lou M, Staals J, Bordet R, Kandiah N, de Leeuw FE, Simister R, van der Lugt A, Kelly PJ, Wardlaw JM, Soo Y, Fluri F, Srikanth V, Calvet D, Jung S, Kwa VIH, Engelter ST, Peters N, Smith EE, Yakushiji Y, Orken DN, Fazekas F, Thijs V, Heo JH, Mok V, Veltkamp R, Ay H, Imaizumi T, Gomez-Anson B, Lau KK, Jouvent E, Rothwell PM, Toyoda K, Bae HJ, Marti-Fabregas J, Werring DJ; Microbleeds International Collaborative Network.

Lancet Neurol. 2019 Jul;18(7):653-665. doi: 10.1016/S1474-4422(19)30197-8. Epub 2019 May 23.

Effects of Mindfulness Yoga vs Stretching and Resistance Training Exercises on Anxiety and Depression for People With Parkinson Disease: A Randomized Clinical Trial

Kwok JYY, Kwan JCY, Auyeung M, Mok VCT, Lau CKY, Choi KC, Chan HYL.

JAMA Neurol. 2019 Jul 1;76(7):755-763. doi: 10.1001/jamaneurol.2019.0534.

Exploring Causal Pathways Linking Cerebral Small Vessel Diseases Burden to Poststroke Depressive Symptoms With Structural Equation Model Analysis

LIANG Y, CHEN YK, LIU YL, MOK VCT, UNGVARI GS, CHU WCW, TANG WK, KIM JS, KIM JM

J Affect Disord. 2019 Jun 15;253:218-223. doi: 10.1016/j.jad.2019.04.092. Epub 2019 Apr 22.

Is Vascular Cognitive Impairment More Common in Asia?

LAM BYK, MOK VCT

Asian J Psychiatr. 2019 Jun;43:202-204. doi: 10.1016/j.ajp.2017.03.043. Epub 2017 Apr 5.

Standardization of hippocampus volumetry using automated brain structure volumetry tool for an initial Alzheimer's disease imaging biomarker

Abrigo J, Shi L, Luo Y, Chen Q, Chu WCW, Mok VCT; Alzheimer’s Disease Neuroimaging Initiative.

Acta Radiol. 2019 Jun;60(6):769-776. doi: 10.1177/0284185118795327. Epub 2018 Sep 5.

Comparison of Multiple Sclerosis Patients With and Without Oligoclonal IgG Bands in South China

LU T, ZHAO L, SUN X, AU C, HUANG Y, YANG Y, BAO J, WU A, KERMODE AG, QIU W, LAU AY

J Clin Neurosci. . 2019 Aug;66:51-55. doi: 10.1016/j.jocn.2019.05.025. Epub 2019 May 30.

Sphenopalatine Ganglion Stimulation to Augment Cerebral Blood Flow: A Randomized, Sham-Controlled Trial

BORNSTEIN NM, SAVER JL, DIENER HC, GORELICK PB, SHUAIB A, SOLBERG Y, DEVLIN T, LEUNG T, MOLINA CA, IMPACT-24A INVESTIGATORS†; IMPACT-24A INVESTIGATORS INCLUDE THE SITE PRINCIPAL INVESTIGATORS, DSMB MEMBERS, AND THE SITE CO-INVESTIGATORS LISTED

Stroke. 2019 May 23;STROKEAHA118024582. doi: 10.1161/STROKEAHA.118.024582. Online ahead of print.

Effectiveness and Cost-Effectiveness of a Virtual Multidisciplinary Stroke Care Clinic for Community-Dwelling Stroke Survivors and Caregivers: A Randomised Controlled Trial Protocol

CHAU JPC, LO SHS, LEE VWY, CHOI KC, SHUM EWC, HUNG ZSS, MOK VCT, SIOW EKC, CHING JYL, LAM SKY, YEUNG JHM, LI SH, LAU AYL

BMJ Open. 2019 May 10;9(5):e026500. doi: 10.1136/bmjopen-2018-026500.

Impact of the Chinese herbal medicines on dual antiplatelet therapy with clopidogrel and aspirin: Pharmacokinetics and pharmacodynamics outcomes and related mechanisms in rats

Xiao M, Qian C, Luo X, Yang M, Zhang Y, Wu C, Mok C, Lee P, Zuo Z

J Ethnopharmacol. 2019 May 10;235:100-110. doi: 10.1016/j.jep.2019.01.040. Epub 2019 Jan 30. PMID: 30710735.

Relapsing Optic Neuritis and Meningoencephalitis in a Child: Case Report of Delayed Diagnosis of MOG-IgG Syndrome

ZHONG X, CHANG Y, TAN S, WANG J, SUN X, WU A, PENG L, LAU AY, KERMODE AG, QIU W

BMC Neurol. 2019 May 9;19(1):94. doi: 10.1186/s12883-019-1324-4. https://pubmed.ncbi.nlm.nih.gov/31072329/

Worldwide Research Trends on Aristolochic Acids (1957-2017): Suggestions for Researchers

ZHOU Q, PEI J, POON J, LAU AY, ZHANG L, WANG Y, LIU C, HUANG L

PLoS One. 2019 May 2;14(5):e0216135. doi: 10.1371/journal.pone.0216135. eCollection 2019.

Hemodynamics and Stroke Risk in Intracranial Atherosclerotic Disease

LENG X, LAN L, IP HL, ABRIGO J, SCALZO F, LIU H, FENG X, CHAN KL, FAN FSY, MA SH, FANG H, XU Y, LI J, ZHANG B, XU Y, SOO YOY, MOK VCT, YU SCH, LIEBESKIND DS, WONG KS, LEUNG TW

Ann Neurol. 2019 May;85(5):752-764. doi: 10.1002/ana.25456. Epub 2019 Apr 3.

Combined Cut-Off Point Determination of F-18-AV-1451 (T807) Imaging Biomarker for Tau Burden and 2018 NIA-AA Definition Facilitate Reclassification of Alzheimer's Disease

HO I, CHEN S, LEUNG YL, CHEUNG MK, HO CL, MOK V

J. Nucl. Med. 2019 May 1;60(1):254.

Seizure and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Encephalomyelitis in a Retrospective Cohort of Chinese Patients

ZHONG X, ZHOU Y, CHANG Y, WANG J, SHU Y, SUN X, PENG L, LAU AY, KERMODE AG, QIU W

Front Neurol. 2019 Apr 26;10:415. doi: 10.3389/fneur.2019.00415. eCollection 2019.

Electromyography Activity Level in Rapid Eye Movement Sleep Predicts Neurodegenerative Diseases in Idiopathic Rapid Eye Movement Sleep Behavior Disorder: A 5-year Longitudinal Study

LIU Y, ZHANG J, LAM SP, YU MWM, LI SX, ZHOU J, CHAN NY, WANG J, FENG H, CHAN A, MOK V, WING YK

Sleep Med. 2019 Apr;56:128-134. doi: 10.1016/j.sleep.2019.01.018. Epub 2019 Jan 28.

Spectral-Domain OCT Measurements in Alzheimer's Disease: A Systematic Review and Meta-analysis

CHAN VTT, SUN Z, TANG S, CHEN LJ, WONG A, THAM CC, WONG TY, CHEN C, IKRAM MK, WHITSON HE, LAD EM, MOK VCT, CHEUNG CY

Ophthalmology. 2019 Apr;126(4):497-510. doi: 10.1016/j.ophtha.2018.08.009. Epub 2018 Aug 13.

Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis

Marini S, Crawford K, Morotti A, Lee MJ, Pezzini A, Moomaw CJ, Flaherty ML, Montaner J, Roquer J, Jimenez-Conde J, Giralt-Steinhauer E, Elosua R, Cuadrado-Godia E, Soriano-Tarraga C, Slowik A, Jagiella JM, Pera J, Urbanik A, Pichler A, Hansen BM, McCauley JL, Tirschwell DL, Selim M, Brown DL, Silliman SL, Worrall BB, Meschia JF, Kidwell CS, Testai FD, Kittner SJ, Schmidt H, Enzinger C, Deary IJ, Rannikmae K, Samarasekera N, Al-Shahi Salman R, Sudlow CL, Klijn CJM, van Nieuwenhuizen KM, Fernandez-Cadenas I, Delgado P, Norrving B, Lindgren A, Goldstein JN, Viswanathan A, Greenberg SM, Falcone GJ, Biffi A, Langefeld CD, Woo D, Rosand J, Anderson CD; International Stroke Genetics Consortium

JAMA Neurol. 2019 Apr 1;76(4):480-491. doi: 10.1001/jamaneurol.2018.4519. PMID: 30726504; PMCID: PMC6459133.

Risk of Intracerebral Haemorrhage in Chinese Patients With Atrial Fibrillation on Warfarin With Cerebral Microbleeds: The IPAAC-Warfarin Study

SOO Y, ABRIGO JM, LEUNG KT, TSANG SF, IP HL, MA SH, MA K, FONG WC, LI SH, LI R, NG PW, WONG KK, LIU W, LAM BYK, WONG KSL, MOK V, CHU WCW, LEUNG TW, IPAAC STUDY GROUP

J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):428-435. doi: 10.1136/jnnp-2018-319104. Epub 2018 Dec 15.

A case-control-family study of idiopathic rapid eye movement sleep behavior disorder

Liu Y, Zhang J, Lam SP, Zhou J, Yu MWM, Li SX, Chan JWY, Postuma RB, Mok VCT, Wing YK

Ann Neurol. 2019 Apr;85(4):582-592. doi: 10.1002/ana.25435. Epub 2019 Mar 19. PMID: 30761606.

Plasma and CSF miRNA dysregulations in subarachnoid hemorrhage reveal clinical courses and underlying pathways

Chan MTH, Wong JYY, Leung AKT, Lu G, Poon WS, Lau AY, Chan WY, Wong GKC

J Clin Neurosci. 2019 Apr;62:155-161. doi: 10.1016/j.jocn.2018.11.038. Epub 2018 Nov 24. PMID: 30482403.

Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis

Yakushiji Y, Wilson D, Ambler G, Charidimou A, Beiser A, van Buchem MA, DeCarli C, Ding D, Gudnason V, Hara H, Imaizumi T, Kohara K, Kwon HM, Launer LJ, Mok V, Phan T, Preis SR, Romero JR, Seshadri S, Srikanth V, Takashima Y, Tsushima Y, Wang Z, Wolf PA, Xiong Y, Yamaguchi S, Werring DJ.

Neurology. 2019 Mar 5;92(10):e1086-e1097. doi: 10.1212/WNL.0000000000007039. Epub 2019 Feb 1.

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

Anderson CS, Huang Y, Lindley RI … Leung WHT … Ngo Van D on behalf of the ENCHANTED Investigators and Coordinators

Lancet. 2019 Mar 2;393(10174):877-888. doi: 10.1016/S0140-6736(19)30038-8. Epub 2019 Feb 7.

Early Identification of High-Risk TIA or Minor Stroke Using Artificial Neural Network

CHAN KL, LENG X, ZHANG W, DONG W, QIU Q, YANG J, SOO Y, WONG KS, LEUNG TW, LIU J

Front Neurol. 2019 Mar 1;10:171. doi: 10.3389/fneur.2019.00171. eCollection 2019.

External Counterpulsation Enhances Neuroplasticity to Promote Stroke Recovery

LIU JY, XIONG L, STINEAR CM, LEUNG H, LEUNG TW, WONG KSL

J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):361-363. doi: 10.1136/jnnp-2018-318185. Epub 2018 May 29.

Evaluation of Novel Parkinson's Disease Candidate Genes in the Chinese Population

CHEW EGY, LIANY H, TAN LCS, AU WL, PRAKASH KM, ANNUAR AA, CHAN AYY, LIM SY, MOK V, CHUNG SJ, SONG K, LIU J, FOO JN, TAN EK

Neurobiol Aging. 2019 Feb;74:235.e1-235.e4. doi: 10.1016/j.neurobiolaging.2018.09.013. Epub 2018 Sep 21.

Brain volume loss can predict cognitive impairments by neuropsychological battery in a cross-sectional study of Chinese patients with multiple sclerosis

MOK VCT, WONG A, LAU AY, ABRIGO J, SHI L

Mult. Scler. J. 2019 Feb ;25(3):442-443. doi: 10.1177/1352458519826874 .

Potential Retinal Biomarkers for Dementia: What Is New?

CHEUNG CY, CHAN VTT, MOK VC, CHEN C, WONG TY

Curr Opin Neurol. 2019 Feb;32(1):82-91. doi: 10.1097/WCO.0000000000000645.

Cortico-Muscular Coherence Modulated by High-Definition Transcranial Direct Current Stimulation in People With Chronic Stroke

Bao SC, Wong WW, Leung TW, Tong KY.

IEEE Trans Neural Syst Rehabil Eng. 2019 Feb;27(2):304-313. doi: 10.1109/TNSRE.2018.2890001. Epub 2018 Dec 27.

Brain Histopathological Study and Prognosis in MOG Antibody-Associated Demyelinating Pseudotumor

SHU Y, LONG Y, WANG S, HU W, ZHOU J, XU H, CHEN C, OU Y, LU Z, LAU AY, YU X, KERMODE AG, QIU W

Ann Clin Transl Neurol. 2019 Jan 8;6(2):392-396. doi: 10.1002/acn3.712. eCollection 2019 Feb.

Vascular dysfunction-The disregarded partner of Alzheimer's disease

Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, Benveniste H, Dichgans M, Iadecola C, Love S, Bath PM, Markus HS, Al-Shahi Salman R, Allan SM, Quinn TJ, Kalaria RN, Werring DJ, Carare RO, Touyz RM, Williams SCR, Moskowitz MA, Katusic ZS, Lutz SE, Lazarov O, Minshall RD, Rehman J, Davis TP, Wellington CL, González HM, Yuan C, Lockhart SN, Hughes TM, Chen CLH, Sachdev P, O'Brien JT, Skoog I, Pantoni L, Gustafson DR, Biessels GJ, Wallin A, Smith EE, Mok V, Wong A, Passmore P, Barkof F, Muller M, Breteler MMB, Román GC, Hamel E, Seshadri S, Gottesman RF, van Buchem MA, Arvanitakis Z, Schneider JA, Drewes LR, Hachinski V, Finch CE, Toga AW, Wardlaw JM, Zlokovic BV

Alzheimers Dement. 2019 Jan;15(1):158-167. doi: 10.1016/j.jalz.2018.07.222. Erratum in: Alzheimers Dement. 2022 Mar;18(3):522. PMID: 30642436; PMCID: PMC6338083.

Early-onset dementia in Chinese: Demographic and etiologic characteristics

AU LWC, WONG A, ABRIGO J, YUEN YP, LEUNG EYL, MOK VCT

Neurol Asia. 2019;24(2):139-146.

Frequency-specific Age-Related Decreased Brain Network Diversity in Cognitively Healthy Elderly: A Whole-Brain Data-Driven Analysis

LOU W, WANG D, WONG A, CHU WCW, MOK VCT, SHI L

Hum Brain Mapp. 2019 Jan;40(1):340-351. doi: 10.1002/hbm.24376. Epub 2018 Sep 21.

A Pharmacokinetic Approach To Herb-Drug Interaction Between Gastrodiae Rhizoma And Carbamazepine In A Model Of Rats

Yip, KL; Koon, CM; Chen, Z; Chook, P; Leung, PC; Schachter, S; Leung, WH; Mok, CT; Leung, H

EPILEPSIA. Year: 2019 Volume: 60 Supplement: 2 Meeting Abstract: P86 Pages: 48-48; Times Cited: 0; IF 6.040, Ranking 20/204.

A Prospective, Longitudinal Study Of Ampa-Antagonist In Chinese Patients With Refractory Epilepsy

Leung, H; Yuen, SL; Ma, K; Ip, B; Ma, SH; Leung, T; Yip, KL; Mok, V

EPILEPSIA. Year: 2019 Volume: 60 Supplement: 2 Meeting Abstract: P267 Pages: 127-128; Times Cited: 0; IF 6.040, Ranking 20/204.

TPK1 mutation induced childhood onset dystonia and dyskinesia

Au, L; Chan, A; Lau, C; Mok, V

MOVEMENT DISORDERS, Year: 2019 Volume: 34 Supplement: 2 Special Issue: SI Meeting Abstract: 412 Pages: S166-S166; Times Cited: 0; IF 8.679, Ranking 11/204. https://www.mdsabstracts.org/abstract/tpk1-mutation-induced-childhood-onset-dystonia-and-dyskinesia/

Bilateral Globus pallidus interna Deep Brain Stimulation in Cranio-Cervical Dystonia (Meige syndrome) patient in Hong Kong

Lau, C; Zhu, C; Chan, D; Ma, K; Au, L; Chan, A; Wong, R; Yeung, J; Poon, W; Mok, V

MOVEMENT DISORDERS. Year: 2019 Volume: 34 Supplement: 2 Special Issue: SI Meeting Abstract: 1302 Pages: S533-S533; Times Cited: 0; IF 8.679, Ranking 11/204

Neurocognitive changes after STN-DBS among PD patients - a 2-year follow-up study in Hong Kong

Tang, V; Chan, D; Zhu, XL; Chan, D; Lau, C; Chan, A; Ma, K; Yeung, J; Mok, V; Poon, W

MOVEMENT DISORDERS. Year: 2019 Volume: 34 Supplement: 2 Special Issue: SI Meeting Abstract: 1737 Pages: 713-714; Times Cited: 0; IF 8.679, Ranking 11/204.

Risk factors associated with 31-day unplanned readmission in 50,912 discharged patients after stroke in China

Wen T, Liu B, Wan X, Zhang X, Zhang J, Zhou X, Lau AYL, Zhang Y

BMC Neurol. 2018 Dec 26;18(1):218. doi: 10.1186/s12883-018-1209-y. PMID: 30587162; PMCID: PMC6306006.. https://pubmed.ncbi.nlm.nih.gov/30587162/

Morphological diversity, protein adsorption, and cellular uptake of polydopamine-coated gold nanoparticles

Sy SKH, Ho LWC, Lau WCY, Ko H, Choi CHJ

Langmuir. 2018 Nov 20;34(46):14033-14045.

Retinal image analytics detects white matter hyperintensities in healthy adults

Lau AY, Mok V, Lee J, Fan Y, Zeng J, Lam B, Wong A, Kwok C, Lai M, Zee B

Ann Clin Transl Neurol. 2018 Nov 15;6(1):98-105. doi: 10.1002/acn3.688. PMID: 30656187; PMCID: PMC6331948.

Oncogenes expand during evolution to withstand somatic amplification

Wang X, Li X, Zhang L, Wong SH, Wang MHT, Tse G, Dai RZW, Nakatsu G, Coker OO, Chen Z, Ko H, Chan JYK, Liu T, Cheng CHK, Cheng ASL, To KF, Plewczynski D, Sung JJY, Yu J, Gin T, Chan MTV, Wu WKK

Ann Oncol. 2018 Nov 1;29(11):2254-2260. doi: 10.1093/annonc/mdy397. PMID: 30204835.

Microvascular resistance and collateral circulation in simulating the stenotic coronary arteries

Liu H, Leung TWH, Shi L

J Appl Physiol (1985). 2018 Oct 1;125(4):1352. doi: 10.1152/japplphysiol.00283.2018. PMID: 30354945.

Comparison of Computerized and Paper-and-Pencil Memory Tests in Detection of Mild Cognitive Impairment and Dementia: A Systematic Review and Meta-analysis of Diagnostic Studies

Chan JYC, Kwong JSW, Wong A, Kwok TCY, Tsoi KKF.

J Am Med Dir Assoc. 2018 Sep;19(9):748-756.e5. doi: 10.1016/j.jamda.2018.05.010. Epub 2018 Jun 18.

Mapping the contribution and strategic distribution patterns of neuroimaging features of small vessel disease in poststroke cognitive impairment

Shi L, Zhao L, Yeung FK, Wong SY, Chan RKT, Tse MF, Chan SC, Kwong YC, Li KC, Liu K, Abrigo JM, Lau AYL, Wong A, Lam BYK, Leung TWH, Fu J, Chu WCW, Mok VCT

J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):918-926. doi: 10.1136/jnnp-2017-317817. Epub 2018 Apr 17. PMID: 29666204.

Correlation of Adventitial Vasa Vasorum with Intracranial Atherosclerosis: A Postmortem Study

Zheng L, Yang WJ, Niu CB, Zhao HL, Wong KS, Leung TWH, Chen XY

J Stroke. 2018 Sep;20(3):342-349. doi: 10.5853/jos.2018.01263. Epub 2018 Sep 30. PMID: 30309229; PMCID: PMC6186920.

High-resolution magnetic resonance vessel wall imaging of chronic intracranial internal carotid artery occlusion

Chen X, Yang W, Chu CW, Wong KS, Leung TWH

J Neuroradiol. 2018 Sep;45(5):336-337. doi: 10.1016/j.neurad.2018.04.005. Epub 2018 May 9. PMID: 29752977.

Strategic infarct location for post-stroke cognitive impairment: A multivariate lesion-symptom mapping study

Zhao L, Biesbroek JM, Shi L, Liu W1, Kuijf HJ, Chu WW, Abrigo JM, Lee RK, Leung TW, Lau AY, Biessels GJ, Mok V, Wong A.

J Cereb Blood Flow Metab. 2018 Aug;38(8):1299-1311. doi: 10.1177/0271678X17728162. Epub 2017 Sep 12.

Correlation of non-vitamin K antagonist oral anticoagulant exposure and cerebral microbleeds in Chinese patients with atrial fibrillation

Soo Y, Abrigo J, Leung KT, Liu W, Lam B, Tsang SF, Ip V, Ma K, Ip B, Ma SH, Fan F, Chu W, Wong L, Mok V, Leung TW.

J Neurol Neurosurg Psychiatry. 2018 Jul;89(7):680-686. doi: 10.1136/jnnp-2017-317151. Epub 2018 Mar 29.

Eye movement parameters and cognitive functions in Parkinson's disease patients without dementia

Wong OW, Chan AY, Wong A, Lau CK, Yeung JH, Mok VC, Lam LC, Chan S.

Parkinsonism Relat Disord. 2018 Jul;52:43-48. doi: 10.1016/j.parkreldis.2018.03.013. Epub 2018 Mar 15.

Marriage and risk of dementia: systematic review and meta-analysis of observational studies

Chen PLH, Mok Vincent VCT.

J NEUROL NEUROSURG PSYCHIATRY. 2018 JUL;89(3):231-238. doi: 10.1136/jnnp-2017-316274.

High prevalence and indexes of anti-John Cunningham virus antibodies in a cohort of Chinese patients with multiple sclerosis.

Lau AYL, Qiu W, Kermode A, Au C, Ng A, Wong A, Ma SH, Au L, Ma K, Ip B, Mok VCT.

Mult Scler J Exp Transl Clin. 2018 Jul-Sep; 4(3): 2055217318788699.

Low Gamma Band Cortico-muscular Coherence Inter-Hemisphere Difference following Chronic Stroke

Bao SC, Wong WW, Leung TW, Tong KY

Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:247-250. doi: 10.1109/EMBC.2018.8512208. PMID: 30440384.

The era after DAWN: treatment of acute ischaemic stroke.

Lau KK, Thomas WH Leung TWH, Soo YOY.

Hong Kong Med J . 2018 Jun;24(3):313–5.

Validity and reliability of two alternate versions of the Montreal Cognitive Assessment (Hong Kong version) for screening of Mild Neurocognitive Disorder

Wong A, Yiu S, Nasreddine Z, Leung KT, Lau A, Soo YOY, Wong LKS, Mok VCT.

PLoS ONE. 2018 May;13(5): e0196344

The Additional Contribution of White Matter Hyperintensity Location to Post-stroke Cognitive Impairment: Insights From a Multiple-Lesion Symptom Mapping Study

Zhao L, Wong A, Luo Y, Liu W, Chu WWC, Abrigo JM, Lee RKL, Mok V, Shi L.

Front Neurosci. 2018 May 1;12:290. doi: 10.3389/fnins.2018.00290. eCollection 2018.

Impact of intracranial artery calcification on cerebral hemodynamic changes.

Wu X, Wang L, Zhong J, Ko J, Shi L, Soo Y, Leung T, Wong KS, Abrigo J, Chen X.

Neuroradiology. 2018 Apr;60(4):357-363. doi: 10.1007/s00234-018-1988-2. Epub 2018 Feb 9.

Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori

Zhang L, Hu W, Cho CH, Chan FK, Yu J, Fitzgerald JR, Cheung CK, Xiao ZG, Shen J, Li LF, Li MX, Wu JC, Ling TK, Chan JY, Ko H, Tse G, Ng SC, Yu S, Wang MH, Gin T, Ashktorab H, Smoot DT, Wong SH, Chan MT, Wu WK

J Pathol. 2018 Apr;244(4):432-444. doi: 10.1002/path.5033. Epub 2018 Feb 28. PMID: 29327342.

Automatic Segmentation of Acute Ischemic Stroke From DWI Using 3-D Fully Convolutional DenseNets

Zhang RZ, Zhao L, Lou WT, Abrigo JM, Mok VCT, Chu WCW, Wang DF, Lin S.

IEEE Transactions on Medical Imaging. 2018 Mar:37(9):2149-2160.

Association Between the Apolipoprotein E Gene Polymorphism and Atherosclerotic Middle Cerebral Artery Stenosis.

Zhang Z, Chen XY, Baum L, Ng HK, Mok V, Wong KS.

Neurologist. 2018 Mar;23(2):47-50. doi: 10.1097/NRL.0000000000000164.

Converting MMSE to MoCA and MoCA 5-minute protocol in an educationally heterogeneous sample with stroke or transient ischemic attack

Wong A, Black SE, Yiu SYP, Au LWC, Lau AYL, Soo YOY, Chan AYY, Leung TWH1, Wong LKS, Kwok TCY, Cheung TCK, Leung KT, Lam BYK, Kwan JSK, Mok VCT.

Int J Geriatr Psychiatry. 2018 May;33(5):729-734. doi: 10.1002/gps.4846. Epub 2018 Jan 2.

Enlarged perivascular spaces in the centrum semiovale are associated with poststroke depression: A 3-month prospective study.

Liang Y, Chan YL, Deng M, Chen YK, Mok V, Wang F, Ungvari GS, Chu CW, Tang WK.

J Affect Disord. 2018 Mar 1;228:166-172. doi: 10.1016/j.jad.2017.11.080. Epub 2017 Nov 22.

Cerebral Small Vessel Disease Burden Is Associated With Poststroke Depressive Symptoms: A 15-Month Prospective Study

Liang Y, Chen YK, Mok VCT, Wang DF, Ungvari GS, Chu WCW, Kang HJ, Tang WK.

Front Aging Neurosci. 2018;10:46.

Vascular cognitive impairment

Flier WM, Skoog I, Julie A. Schneider JA, Pantoni L, Mok VCT, Chen CLH, Scheltens P.

Nat Rev Dis Primers. 2018 Feb; 18003.

Antiplatelet therapy after stroke: should it differ in the acute and chronic phase after stroke

Leng X, Leung TW, Wong KSL.

Curr Opin Neurol. 2018 Feb;31(1):14-22. doi: 10.1097/WCO.0000000000000509.

Long-Term Evolutionary Change in the Lumen of Intracranial Atherosclerotic Stenosis Following Angioplasty and Stenting

Yu SCH, Lau TWW, Wong SSM, Lee KT, Wong LKS, Leung TWH.

Oper Neurosurg (Hagerstown). 2018 Feb 1;14(2):128-138. doi: 10.1093/ons/opx097.

Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis.

Leng X, Lan L, Ip HL, Fan F, Ma SH, Ma K, Liu H, Yan Z, Liu J, Abrigo J, Soo YOY, Liebeskind DS, Wong KS, Leung TW.

Eur J Neurol. 2018 Feb;25(2):404-410. doi: 10.1111/ene.13521. Epub 2017 Dec 18.

Effects of Acupuncture on the Recovery Outcomes of Stroke Survivors with Shoulder Pain: A Systematic Review.

Chau JPC, Lo SHS, Yu X, Choi KC, Lau AYL, Wu JCY, Lee VWY, Cheung WHN, Ching JYL, Thompson DR.

Front Neurol. 2018 Jan 31;9:30. doi: 10.3389/fneur.2018.00030. eCollection 2018.

White Matter Hyperintensity Predicts the Risk of Incident Cognitive Decline in Community Dwelling Elderly

Ding D, Xiong Y, Zhao Q, Guo Q, Chu S, Chu WWC, Luo J, Liang X, Zheng L, Hong Z, Wong LKS, Mok VCT.

J Alzheimers Dis. 2018;61(4):1333-1341. doi: 10.3233/JAD-170876.

Morphological Evolution or Symptomatic Irltracranial A herosclerotic Plaques: a 10-year Longitudinal Study by 3-Dimensional Rotational Angiography

Leng XY, Wang L, Zou XY, Soo YOY, Chan AYY, Ip VHL, Fan FSY, Mok CT, Wong LKS, Yu SCH, Leung TWH.

Stroke. 2018;49:A86.

Morphology of Acute Symptomatic Intracranial Atherosclerotic Plaques

Leng XY, Wang L, Zou XY, Soo YOY, Chan AYY, Ip VHL, Fan FSY, Mok CT, Wong LKS, Yu SCH, Leung TWH.

Stroke. 2018;49:ATP127.

Postmortem Study Exploring Distribution and Patterns of Intracranial Arterial Calcification.

Yang WJ, Zheng L, Wu XH, Niu CB, W Leung TW, Chen XY.

Stroke. 2018;49:AWMP44.

Use of Acupuncture to Reduce Hemiplegic Shoulder Pain is Feasible and Acceptable among Community-Dwelling Stroke Survivors.

Chau JPC, Lo SHS, Lau AYL, Wu JCY, Cheung WHN, Ching JYL, Choi KC, Lee VWY, Sit JWH, Thompson DR.

Stroke. 2018;49:ATP152.

Estimating current and long-term risks of coronary artery in silico by fractional flow reserve, wall shear stress and low-density lipoprotein filtration rate

Haipeng Liu1,2,5, Yinglan Gong3,5, Xinyi Leng1, Ling Xia3, Ka Sing Wong1, Shanxing Ou4, Thomas W Leung1,6, Defeng Wang2 and Lin Shi2,6

Biomedical Physics & Engineering Express. 2018 Jan;4(2).

Preliminary Results of An Observational Study to Evaluate Integrative Medicine in Managing Fatigue and Cognitive Deficits Associated with Multiple Sclerosis

Ng A, Lam M, Au C, Yuen D, Cheung W, Hung Z, Lin WL, Chung V, Wong A, Chan J, Poon S, Poon J, Mok V, Wu J, Lau A.

Mult Scler J. 2018; 402-403.

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O7, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM5, Mattsson N7, Kornhuber J, Sabri O, Rowe CC, Parnetti L, Popp J, Fladby T, Jagust WJ5, Aalten P1, Lee DY, Vandenberghe R, Resende de Oliveira C, Kapaki E, Froelich L, Ivanoiu A, Gabryelewicz T, Verbeek MM, Sanchez-Juan P, Hildebrandt H, Camus V, Zboch M, Brooks DJ, Drzezga A, Rinne JO, Newberg A, de Mendonça A, Sarazin M, Rabinovici GD, Madsen K, Kramberger MG, Nordberg A, Mok V, Mroczko B, Wolk DA, Meyer PT, Tsolaki M, Scheltens P, Verhey FRJ, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BNM3, Blennow K, van Buchem MA, Cavedo E, Chen K, Chipi E, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gkatzima O, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Johannsen P, Klimkowicz-Mrowiec A, Köhler S, Koglin N, van Laere K, de Leon M, Lisetti V, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Nordlund A, Novak GP, Paraskevas GP, Perera G, Peters O, Ramakers IHGB, Rami L, Rodríguez-Rodríguez E, Roe CM, Rot U, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE8, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Zetterberg H.

JAMA Psychiatry. 2018 Jan 1;75(1):84-95. doi: 10.1001/jamapsychiatry.2017.3391.

Autonomic Dysfunction Predicts Clinical Outcomes After Acute Ischemic Stroke: A Prospective Observational Study.

Xiong L, Tian G, Leung H, Soo YOY, Chen X, Ip VHL, Mok VCT, Chu WCW, Wong KS, Leung TWH.

Stroke. 2018 Jan;49(1):215-218. doi: 10.1161/STROKEAHA.117.019312. Epub 2017 Dec 4.

Impact of Side Branches on the Computation of Fractional Flow in Intracranial Arterial Stenosis Using the Computational Fluid Dynamics Method.

Liu H, Lan L, Leng X, Ip HL, Leung TWH, Wang D, Wong KS.

J Stroke Cerebrovasc Dis. 2018 Jan;27(1):44-52. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.032. Epub 2017 Oct 27.

Impact of Side Branches on the Computation of Fractional Flow in Intracranial Arterial Stenosis Using the Computational Fluid Dynamics Method

Liu H, Lan L, Leng X, Ip HL, Leung TWH, Wang D, Wong KS

J Stroke Cerebrovasc Dis. 2018 Jan;27(1):44-52. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.032. Epub 2017 Oct 27. PMID: 29107636.

The Association Between Diabetes and Olfactory Function in Adults

Chan JYK, García-Esquinas E, Ko OH, Tong MCF, Lin SY

Chem Senses. 2017 Dec 25;43(1):59-64. doi: 10.1093/chemse/bjx070. PMID: 29126164.

Cerebral perfusion difference between hemispheres with symptomatic and asymptomatic intracranial arterial stenosis.

Lan L, Leng X, Abrigo J, Ip V, Soo YO, Leung T, Chen X, Wong KS.

Int J Stroke. 2017 Dec;12(9):NP19-NP20. doi: 10.1177/1747493016676284. Epub 2016 Oct 20.

Brain microbleeds, anticoagulation, and hemorrhage risk: Meta-analysis in stroke patients with AF

Charidimou A, Karayiannis C, Song TJ, Orken DN, Thijs V, Lemmens R, Kim J, Goh SM, Phan TG, Soufan C, Chandra RV, Slater LA, Haji S, Mok V, Horstmann S, Leung KT, Kawamura Y, Sato N, Hasebe N, Saito T, Wong LKS, Soo Y, Veltkamp R, Flemming KD, Imaizumi T, Srikanth V, Heo JH

Neurology. 2017 Dec 5;89(23):2317-2326. doi: 10.1212/WNL.0000000000004704.

Enlarged perivascular spaces are associated with health-related quality of life in patients with acute ischemic stroke

Liang Y, Deng M, Chen YK, Mok V, Wang DF, Ungvari GS, Chu CW, Berge E, Tang WK

CNS Neurosci Ther. 2017 Dec;23(12):973-979. doi: 10.1111/cns.12766.

Minimum Clinically Important Difference of Montreal Cognitive Assessment in aneurysmal subarachnoid hemorrhage patients.

Wong GKC, Mak JSY, Wong A, Zheng VZY, Poon WS, Abrigo J, Mok VCT.

J Clin Neurosci. 2017 Dec;46:41-44. doi: 10.1016/j.jocn.2017.08.039. Epub 2017 Sep 5.

Early versus Late Application of Subthalamic deep brain Stimulation to Parkinson's disease patients with motor complications (ELASS): protocol of a multicentre, prospective and observational study

Jiang L, Poon WS, Moro E, Xian W, Yang C, Zhu XL, Gu J, Cai X, Liu J, Mok V, Liu Y, Xu S, Guo Q, Chen W, Chen L

BMJ Open. 2017 Nov 16;7(11):e018610. doi: 10.1136/bmjopen-2017-018610.

The Spatial Associations of Cerebral Blood Flow and Spontaneous Brain Activities with White Matter Hyperintensities-An Exploratory Study Using Multimodal Magnetic Resonance Imaging.

Shi L, Miao X, Lou W, Liu K, Abrigo J, Wong A, Chu WCW, Wang D, Mok VCT.

Front Neurol. 2017 Nov 9;8:593. doi: 10.3389/fneur.2017.00593. eCollection 2017.

Using Retinal Imaging to Study Dementia

Chan VTT, Tso THK, Tang F, Tham C, Mok V, Chen C, Wong TY, Cheung CY

J Vis Exp. 2017 Nov 6;(129). doi: 10.3791/56137.

Association of Cerebral Small Vessel Disease Burden and Health-Related Quality of Life after Acute Ischemic Stroke.

Liang Y, Chen YK, Deng M, Mok VCT, Wang DF, Ungvari GS, Chu CW, Kamiya A, Tang WK.

Front Aging Neurosci. . 2017 Nov 13;9:372. doi: 10.3389/fnagi.2017.00372. eCollection 2017.

The effects of yoga versus stretching and resistance training exercises on psychological distress for people with mild-to-moderate Parkinson’s disease: study protocol for a randomized controlled trial

Kwok JYY, Kwan JCY, Auyeung M, Mok VCT, Chan HYL

Trials. 2017;18(1):509.

Current status of home blood pressure monitoring in Asia: Statement from the HOPE Asia Network

Chia YC1, Buranakitjaroen P, Chen CH, Divinagracia R, Hoshide S, Park S, Shin J, Siddique S, Sison J, Soenarta AA, Sogunuru GP, Tay JC, Turana Y, Wang JG, Wong L, Zhang Y, Kario K; HOPE Asia Network

J Clin Hypertens (Greenwich). 2017 Nov;19(11):1192-1201. doi: 10.1111/jch.13058. Epub 2017 Aug 17.

Cognitive profiles in Hong Kong Chinese with relapsing and progressive multiple sclerosis.

Lau AY, Ng A, Au C, Yuen KY, Mok V, Wu JC, Wong A.

MULT SCLER J. 2017 Oct; 23:764.

A retrospective, cross sectional controlled study of Chinese medicine for post-stroke rehabilitation.

Ma CH, Li LSW, Kwok LP, Tsang KWY, Cheng MCK, Mok VCT, Or KKH, Zhang ZJ.

J Neurol Sci. 2017 OCT 15;381:923.

Prevalence of neutralising antibodies to interferon-beta and clinical response in Chinese patients with relapsing multiple sclerosis.

Lau AY, Ip WK, Au C, Lau KK, Wong W, Yip KK, Yeung J, Li SH, Li P, Lee R, Siu D, Abrigo J, Wong A, Mok V, Chan E.

Mult Scler J Exp Transl Clin. 2017 Oct 9;3(4):2055217317733485. doi: 10.1177/2055217317733485. eCollection 2017 Oct-Dec.

Noninvasive fractional flow in intracranial atherosclerotic stenosis: Reproducibility, limitations, and perspectives.

Leng X, Lan L, Ip VHL, Liu H, Abrigo J, Liebeskind DS, Wong LKS, Leung TW.

J Neurol Sci. 2017 Oct 15;381:150-152. doi: 10.1016/j.jns.2017.08.3239. Epub 2017 Aug 24.

Smartphone electrographic monitoring for atrial fibrillation in acute ischemic stroke and transient ischemic attack

Tu HT, Chen Z, Swift C, Churilov L, Guo R, Liu X, Jannes J, Mok V, Freedman B, Davis SM, Yan B.

Int J Stroke. 2017 Oct;12(7):786-789. doi: 10.1177/1747493017696097. Epub 2017 Mar 8.

Acute basilar artery occlusion: Endovascular Interventions versus Standard Medical Treatment (BEST) Trial-Design and protocol for a randomized, controlled, multicenter study

Liu X, Xu G, Liu Y, Zhu W, Ma M, Xiong Y, Zi W, Dai Q, Leung T, Yan B, Davis S, Liebeskind DS, Pereira VM, Nogueira RG; BEST Trial Investigators

Int J Stroke. 2017 Oct;12(7):779-785. doi: 10.1177/1747493017701153. Epub 2017 Mar 31. PMID: 28361616.

Development and validation of a risk score (CHANGE) for cognitive impairment after ischemic stroke

Chander RJ, Lam BYK, Lin X, Ng AYT, Wong APL, Mok VCT, Kandiah N

Sci Rep. 2017 Sep 29;7(1):12441. doi: 10.1038/s41598-017-12755-z.

Histological Characteristics of Intracranial Atherosclerosis in a Chinese Population: A Postmortem Study.

Yang WJ, Fisher M, Zheng L, Niu CB, Paganini-Hill A, Zhao HL, Xu Y, Wong KS, NG HK, Chen XY.

Front Neurol. 2017;8:488.

Age-specific trends of atrial fibrillation-related ischaemic stroke and transient ischaemic attack, anticoagulant use and risk factor profile in Chinese population: a 15-year study

Soo Y, Chan N, Leung KT, Chen XY, Mok V, Wong L, Leung T

J Neurol Neurosurg Psychiatry. 2017 Sep;88(9):744-748. doi: 10.1136/jnnp-2017-315735.

Recall Tests Are Effective to Detect Mild Cognitive Impairment: A Systematic Review and Meta-analysis of 108 Diagnostic Studies.

Tsoi KKF, Chan JYC, Hirai HW, Wong A, Mok VCT, Lam LCW, Kwok TCY, Wong SYS.

J Am Med Dir Assoc. 2017 Sep 1;18(9):807.e17-807.e29. doi: 10.1016/j.jamda.2017.05.016. Epub 2017 Jul 25.

Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging.

Yang WJ, Wong KS, Chen XY.

J Stroke. 2017 Sep;19(3):249-260. doi: 10.5853/jos.2016.01956. Epub 2017 Sep 6.

Computerized Cognitive Screen (CoCoSc): A Self-Administered Computerized Test for Screening for Cognitive Impairment in Community Social Centers

Wong A, Fong CH, Mok VC, Leung KT, Tong RK

J Alzheimers Dis. 2017;59(4):1299-1306. doi: 10.3233/JAD-170196.

Using Large-Scale Statistical Chinese Brain Template (Chinese2020) in Popular Neuroimage Analysis Toolkits

Shi L, Liang PP, Luo Y, Liu K, Mok VCT, Chu WCW, Wang DF, Li KC.

Frontiers in Human Neuroscience. 2017;11:6.

Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries

Hilal S1, Mok V, Youn YC, Wong A, Ikram MK5, Chen CL

J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):669-674. doi: 10.1136/jnnp-2016-315324. Epub 2017 Jun 9.

Cortical Microinfarcts in Patients with Middle Cerebral Artery Stenosis.

Leng X, Fang H, Pu Y, Zou X, Pan Y, Soo YOY, Xu Y, Wang C, Zhao X, Wang Y, Wang Y, Liebeskind DS, Wong LKS, Leung TW6, Liu L.

J Stroke Cerebrovasc Dis. 2017 Aug;26(8):1760-1765. doi: 10.1016/j.jstrokecerebrovasdis.2017.04.002. Epub 2017 May 15.

External Counterpulsation Increases Beat-to-Beat Heart Rate Variability in Patients with Ischemic Stroke.

Xiong L1, Tian G, Wang L, Lin W, Chen X, Leung TWH, Soo YOY, Wong LKS.

J Stroke Cerebrovasc Dis. 2017 Jul;26(7):1487-1492. doi: 10.1016/j.jstrokecerebrovasdis.2017.03.007. Epub 2017 Apr 7.

Prediction of Recurrent Stroke or Transient Ischemic Attack After Noncardiogenic Posterior Circulation Ischemic Stroke.

Zhang C, Wang Y, Zhao X, Liu L, Wang C, Pu Y, Zou X, Pan Y, Wong KS, Wang Y; Chinese IntraCranial AtheroSclerosis (CICAS) Study Group.

Stroke. 2017 Jul;48(7):1835-1841. doi: 10.1161/STROKEAHA.116.016285. Epub 2017 Jun 16.

Refinement of learned skilled movement representation in motor cortex deep output layer

Li Q, Ko H, Qian ZM, Yan LYC, Chan DCW, Arbuthnott G, Ke Y, Yung WH

Nature communications. 2017 Jun 9;8:15834. doi: 10.1038/ncomms15834. PMID: 28598433; PMCID: PMC5472789.

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org

Hoshino T, Uchiyama S, Wong LKS, Sissani L, Albers GW, Bornstein NM, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Labreuche J, Lavallée PC, Molina C, Rothwell PM, Steg PG, Touboul PJ, Vicaut É, Amarenco P; TIAregistry.org Investigators.

Stroke. 2017 Jul;48(7):1779-1787. doi: 10.1161/STROKEAHA.117.016874. Epub 2017 Jun 5.

Impaired cerebral autoregulation: measurement and application to stroke.

Xiong L, Liu X, Shang T, Smielewski P, Donnelly J, Guo ZN, Yang Y, Leung T, Czosnyka M, Zhang R, Liu J, Wong KS.

J Neurol Neurosurg Psychiatry. 2017 Jun;88(6):520-531. doi: 10.1136/jnnp-2016-314385.

A Randomized Controlled Trial of Chinese Medicine on Nonmotor Symptoms in Parkinson's Disease

Ka-Kit Chua, Adrian Wong, Kam-Wa Chan, Yin-Kei Lau, Zhao-Xiang Bian, Jia-Hong Lu, Liang-Feng Liu, Lei-Lei Chen, Ka-Ho Chan, Kim-Pong Tse,1 Anne Chan, Ju-Xian Song, Justin Wu, Li-Xing Zhu, Vincent Mok, and Min Li1

Parkinsons Dis. 2017;2017:1902708.

Excessive Daytime Sleepiness Predicts Neurodegeneration in Idiopathic REM Sleep Behavior Disorder

Zhou J, Zhang J, Lam SP, Chan JW, Mok V, Chan A, Li SX4, Liu Y, Tang X, Yung WH, Wing YK

Sleep. 2017 May 1;40(5). doi: 10.1093/sleep/zsx041.

Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke?

Xiong L, Tian G, Lin W, Wang W, Wang L, Leung T, Mok V, Liu J, Chen X, Wong KS

J Stroke Cerebrovasc Dis. 2017 May;26(5):1081-1087. doi: 10.1016/j.jstrokecerebrovasdis.2016.12.024.

Intracerebral hemorrhage location and outcome among INTERACT2 participants

Delcourt C, Sato S, Zhang S, Sandset EC, Zheng D, Chen X, Hackett ML, Arima H, Hata J, Heeley E, Al-Shahi Salman R, Robinson T, Davies L, Lavados PM, Lindley RI, Stapf C, Chalmers J, Anderson CS; INTERACT2 Investigators

Neurology. 2017 Apr 11;88(15):1408-1414. doi: 10.1212/WNL.0000000000003771. Epub 2017 Feb 24. PMID: 28235817; PMCID: PMC5386433.

Location of Acute Infarcts and Agitation and Aggression in Stroke

Tang WK, Liu XX, Liang H, Chen YK, Chu WCW, Ahuja AT, Abrigo J, Mok VCT, Ungvari GS, Wong KS, Spalletta G

J Neuropsychiatry Clin Neurosci. 2017 Spring;29(2):172-178. doi: 10.1176/appi.neuropsych.15110400.

Neuroticism and Fatigue 3 Months After Ischemic Stroke: A Cross-Sectional Study.

Lau CG, Tang WK, Liu XX, Liang HJ, Liang Y, Mok V, Wong A, Ungvari GS, Kutlubaev MA, Wong KS.

Arch Phys Med Rehabil. 2017 Apr;98(4):716-721. doi: 10.1016/j.apmr.2016.08.480. Epub 2016 Sep 24.

Intracranial atherosclerosis: From anatomy to pathophysiology.

Pu Y, Lan L, Leng X, Wong LK, Liu L.

Int J Stroke. 2017 Apr;12(3):236-245. doi: 10.1177/1747493016685716. Epub 2017 Jan 9.

Early-onset and delayed-onset poststroke dementia - revisiting the mechanisms

Mok VC, Lam BY, Wong A, Ko H, Markus HS, Wong LK

Nat Rev Neurol. 2017 Mar;13(3):148-159. doi: 10.1038/nrneurol.2017.16.

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting.

Hobeanu C, Lavallée PC, Rothwell PM, Sissani L, Albers GW, Bornstein NM, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Labreuche J, Molina C, Steg PG, Touboul PJ, Uchiyama S, Vicaut É, Wong LK, Amarenco P; TIAregistry.org Investigators.

Stroke. 2017 Apr;48(4):1005-1010. doi: 10.1161/STROKEAHA.116.015171. Epub 2017 Mar 13.

Group comparison of cortical fiber connectivity map: An application between post-stroke patients and healthy subjects.

Liu K, Zhang T, Chu WC, Mok VC, Wang D, Shi L

Neuroscience. 2017 Mar 6;344:15-24. doi: 10.1016/j.neuroscience.2016.12.026.

Poststroke agitation and aggression and social quality of life: a case control study.

Lau CG, Tang WK, Liu XX, Liang HJ, Liang Y, Wong A, Mok V, Ungvari GS, Wong KS, Kim JS, Paradiso S.

Top Stroke Rehabil. 2017 Mar;24(2):126-133. doi: 10.1080/10749357.2016.1212564. Epub 2016 Sep 7.

Clinical Features of Thalamic Stroke

Chen XY, Wang Q, Wang X, Wong KS

Curr Treat Options Neurol . 2017 Feb;19(2):5. doi: 10.1007/s11940-017-0441-x.

Limb girdle myasthenia with digenic RAPSN and a novel disease gene AK9 mutations

Lam CW, Wong KS, Leung HW, Law CY.

Eur J Hum Genet. 2017 Feb;25(2):192-199. doi: 10.1038/ejhg.2016.162. Epub 2016 Dec 14.

High Extent of Intracranial Carotid Artery Calcification Is Associated with Downstream Microemboli in Stroke Patients.

Wu XH, Chen XY, Fan YH, Leung TW, Wong KS.

J Stroke Cerebrovasc Dis. 2017 Feb;26(2):442-447. doi: 10.1016/j.jstrokecerebrovasdis.2016.10.007. Epub 2016 Nov 3.

Cross-Cultural Differences of the Non-Motor Symptoms Studied by the Traditional Chinese Version of the International Parkinson and Movement Disorder Society- Unified Parkinson's Disease Rating Scale

Yu RL1, Wu RM, Chan AY, Mok V, Wu YR, Tilley BC, Luo S, Wang L, LaPelle NR, Stebbins GT, Goetz CG

Mov Disord Clin Pract. 2017 Jan-Feb;4(1):68-77. doi: 10.1002/mdc3.12349.

Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study

Wang L, Heckman MG, Aasly JO, Annesi G, Bozi M, Chung SJ, Clarke C, Crosiers D, Eckstein G, Garraux G, Hadjigeorgiou GM, Hattori N, Jeon B, Kim YJ, Kubo M, Lesage S, Lin JJ, Lynch T, Lichtner P, Mellick GD, Mok V, Morrison KE, Quattrone A, Satake W, Silburn PA, Stefanis L, Stockton JD, Tan EK, Toda T, Brice A, Van Broeckhoven C, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, Gasser T, Krüger R, Farrer MJ, Ross OA, Sharma M

Neurobiol Aging. 2017 Jan;49:217.e1-217.e4. doi: 10.1016/j.neurobiolaging.2016.09.022.

Genome-wide association study of Parkinson's disease in East Asians

Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, Aung T, Cheng CY, Chew FT, Chew SH, Chong SA, Ebstein RP, Lee J, Saw SM, Seow A, Subramaniam M, Tai ES, Vithana EN, Wong TY, Heng KK, Meah WY, Khor CC, Liu H, Zhang F, Liu J, Tan EK

Hum Mol Genet. 2017 Jan 1;26(1):226-232. doi: 10.1093/hmg/ddw379.

Deep Cascaded Networks for Sparsely Distributed Object Detection from Medical Images

Chen, H Dou, Q Yu, L Qin, J Zhao, L Mok, VCT Wang, D Shi, L Heng, PA

Deep Learning for Medical Image Analysis. 2017:(6):133-135.

A 5-Year Longitudinal Study of Cognitive Decline After Stroke/Transient Ischemic Attack (CU-STRIDE).

Lam B, Wong A, Wang ZL, Liu WY, Au L, Chan A, Lau A, Shi L, Fan F, Ma SH, Ip V, Soo Y, Leung T, Leng XY, Chen XY, Chu W, Mok V.

Cerebrovasc Dis. 2017;44(S1):4.

Prolonged Perfusion Predicts Recurrent Ischemic Stroke but not Transient Ischemic Attack in Patients with Symptomatic Intracranial Stenosis.

Lan L, Leng X, Ip V, Leung T, Soo Y, Abrigo J, Wong KS.

Curr Neurovasc Res. 2017;14(2):149-157. doi: 10.2174/1567202614666170413143203.

The prognosis of acute symptomatic seizures after ischaemic stroke.

Leung T, Leung H, Soo YO, Mok VC, Wong KS.

J Neurol Neurosurg Psychiatry. 2017 Jan;88(1):86-94. doi: 10.1136/jnnp-2015-311849. Epub 2016 Jan 27.

Benign Oligemia in Subacute Stage Is Associated with Borderzone Infarction in Stroke Patients Caused by Intracranial Large Artery Disease

Li J, Chen XY, Soo Y, Leung TW, Zeng J, Wong KS.

Eur Neurol. 2017;77(1-2):80-86. doi: 10.1159/000454678. Epub 2016 Dec 14.

Morphometry analysis of basal ganglia structures in children with obstructive sleep apnea.

Lv J, Shi L, Zhao L, Weng J, Mok VC, Chu WC, Wang D.

J Xray Sci Technol. 2017;25(1):93-99. doi: 10.3233/XST-16171.

Sex Differences Do Not Exist in Outcomes among Stroke Patients with Intracranial Atherosclerosis in China: Subgroup Analysis from the Chinese Intracranial Atherosclerosis Study

Pu Y, Wei N, Yu D, Wang Y, Zou X, Soo YOY, Pan Y, Leung TWH, Wong LKS, Wang Y, Liu L.

Neuroepidemiology. 2017;18(1-2):48-54.

Association studies of genetic polymorphism and environmental factors in ischemic stroke with atherosclerotic middle cerebral artery stenosis.

Zhang ZS, Chen XY, Baum L, Ng HK, Mok V, Wong KS.

Neurology Asia. 2017;22(4):291-297.

Principles of precision medicine in stroke

Hinman JD, Rost NS, Leung TW, Montaner J, Muir KW, Brown S, Arenillas JF, Feldmann E, Liebeskind DS

J Neurol Neurosurg Psychiatry. 2017 Jan;88(1):54-61. doi: 10.1136/jnnp-2016-314587. Epub 2016 Oct 19. PMID: 27919057.