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Publications

2018

Cognitive Disorders

Comparison of Computerized and Paper-and-Pencil Memory Tests in Detection of Mild Cognitive Impairment and Dementia: A Systematic Review and Meta-analysis of Diagnostic Studies.

Chan JYC, Kwong JSW, Wong A, Kwok TCY, Tsoi KKF.
J Am Med Dir Assoc. 2018 Sep;19(9):748-756.e5. doi: 10.1016/j.jamda.2018.05.010. Epub 2018 Jun 18.
Stroke & Cerebrovascular Diseases
 
Cognitive Disorders

Strategic infarct location for post-stroke cognitive impairment: A multivariate lesion-symptom mapping study

Zhao L, Biesbroek JM, Shi L, Liu W1, Kuijf HJ, Chu WW, Abrigo JM, Lee RK, Leung TW, Lau AY, Biessels GJ, Mok V, Wong A.
J Cereb Blood Flow Metab. 2018 Aug;38(8):1299-1311. doi: 10.1177/0271678X17728162. Epub 2017 Sep 12.
Stroke & Cerebrovascular Diseases

Correlation of non-vitamin K antagonist oral anticoagulant exposure and cerebral microbleeds in Chinese patients with atrial fibrillation.

Soo Y, Abrigo J, Leung KT, Liu W, Lam B, Tsang SF, Ip V, Ma K, Ip B, Ma SH, Fan F, Chu W, Wong L, Mok V, Leung TW.
J Neurol Neurosurg Psychiatry. 2018 Jul;89(7):680-686. doi: 10.1136/jnnp-2017-317151. Epub 2018 Mar 29.
Parkinson’s Disease & Movement Disorders

Eye movement parameters and cognitive functions in Parkinson's disease patients without dementia.

Wong OW, Chan AY, Wong A, Lau CK, Yeung JH, Mok VC, Lam LC, Chan S.
Parkinsonism Relat Disord. 2018 Jul;52:43-48. doi: 10.1016/j.parkreldis.2018.03.013. Epub 2018 Mar 15.
Cognitive Disorders

Marriage and risk of dementia: systematic review and meta-analysis of observational studies

Chen PLH, Mok Vincent VCT.
J NEUROL NEUROSURG PSYCHIATRY. 2018 JUL;89(3):231-238. doi: 10.1136/jnnp-2017-316274.
Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders

High prevalence and indexes of anti-John Cunningham virus antibodies in a cohort of Chinese patients with multiple sclerosis.

Lau AYL, Qiu W, Kermode A, Au C, Ng A, Wong A, Ma SH, Au L, Ma K, Ip B, Mok VCT.
Mult Scler J Exp Transl Clin. 2018 Jul-Sep; 4(3): 2055217318788699.
Stroke & Cerebrovascular Diseases

The era after DAWN: treatment of acute ischaemic stroke.

Lau KK, Thomas WH Leung TWH, Soo YOY.
Hong Kong Med J . 2018 Jun;24(3):313–5.
Cognitive Disorders

Validity and reliability of two alternate versions of the Montreal Cognitive Assessment (Hong Kong version) for screening of Mild Neurocognitive Disorder

Wong A, Yiu S, Nasreddine Z, Leung KT, Lau A, Soo YOY, Wong LKS, Mok VCT.
PLoS ONE. 2018 May;13(5): e0196344
Cognitive Disorders

The Additional Contribution of White Matter Hyperintensity Location to Post-stroke Cognitive Impairment: Insights From a Multiple-Lesion Symptom Mapping Study

Zhao L, Wong A, Luo Y, Liu W, Chu WWC, Abrigo JM, Lee RKL, Mok V, Shi L.
Front Neurosci. 2018 May 1;12:290. doi: 10.3389/fnins.2018.00290. eCollection 2018.
Others

Impact of intracranial artery calcification on cerebral hemodynamic changes.

Wu X, Wang L, Zhong J, Ko J, Shi L, Soo Y, Leung T, Wong KS, Abrigo J, Chen X.
Neuroradiology. 2018 Apr;60(4):357-363. doi: 10.1007/s00234-018-1988-2. Epub 2018 Feb 9.
Stroke & Cerebrovascular Diseases

Automatic Segmentation of Acute Ischemic Stroke From DWI Using 3-D Fully Convolutional DenseNets

Zhang RZ, Zhao L, Lou WT, Abrigo JM, Mok VCT, Chu WCW, Wang DF, Lin S.
IEEE Transactions on Medical Imaging. 2018 Mar:37(9):2149-2160.
Stroke & Cerebrovascular Diseases

Association Between the Apolipoprotein E Gene Polymorphism and Atherosclerotic Middle Cerebral Artery Stenosis.

Zhang Z, Chen XY, Baum L, Ng HK, Mok V, Wong KS.
Neurologist. 2018 Mar;23(2):47-50. doi: 10.1097/NRL.0000000000000164.
Cognitive Disorders

Converting MMSE to MoCA and MoCA 5-minute protocol in an educationally heterogeneous sample with stroke or transient ischemic attack

Wong A, Black SE, Yiu SYP, Au LWC, Lau AYL, Soo YOY, Chan AYY, Leung TWH1, Wong LKS, Kwok TCY, Cheung TCK, Leung KT, Lam BYK, Kwan JSK, Mok VCT.
Int J Geriatr Psychiatry. 2018 May;33(5):729-734. doi: 10.1002/gps.4846. Epub 2018 Jan 2.
Stroke & Cerebrovascular Diseases

Enlarged perivascular spaces in the centrum semiovale are associated with poststroke depression: A 3-month prospective study.

Liang Y, Chan YL, Deng M, Chen YK, Mok V, Wang F, Ungvari GS, Chu CW, Tang WK.
J Affect Disord. 2018 Mar 1;228:166-172. doi: 10.1016/j.jad.2017.11.080. Epub 2017 Nov 22.
Stroke & Cerebrovascular Diseases
 
Cognitive Disorders

Cerebral Small Vessel Disease Burden Is Associated With Poststroke Depressive Symptoms: A 15-Month Prospective Study

Liang Y, Chen YK, Mok VCT, Wang DF, Ungvari GS, Chu WCW, Kang HJ, Tang WK.
Front Aging Neurosci. 2018;10:46.
Cognitive Disorders

Vascular cognitive impairment

Flier WM, Skoog I, Julie A. Schneider JA, Pantoni L, Mok VCT, Chen CLH, Scheltens P.
Nat Rev Dis Primers. 2018 Feb; 18003.
Stroke & Cerebrovascular Diseases

Antiplatelet therapy after stroke: should it differ in the acute and chronic phase after stroke

Leng X, Leung TW, Wong KSL.
Curr Opin Neurol. 2018 Feb;31(1):14-22. doi: 10.1097/WCO.0000000000000509.
Others

Long-Term Evolutionary Change in the Lumen of Intracranial Atherosclerotic Stenosis Following Angioplasty and Stenting

Yu SCH, Lau TWW, Wong SSM, Lee KT, Wong LKS, Leung TWH.
Oper Neurosurg (Hagerstown). 2018 Feb 1;14(2):128-138. doi: 10.1093/ons/opx097.
Stroke & Cerebrovascular Diseases

Translesional pressure gradient and leptomeningeal collateral status in symptomatic middle cerebral artery stenosis.

Leng X, Lan L, Ip HL, Fan F, Ma SH, Ma K, Liu H, Yan Z, Liu J, Abrigo J, Soo YOY, Liebeskind DS, Wong KS, Leung TW.
Eur J Neurol. 2018 Feb;25(2):404-410. doi: 10.1111/ene.13521. Epub 2017 Dec 18.
Stroke & Cerebrovascular Diseases

Effects of Acupuncture on the Recovery Outcomes of Stroke Survivors with Shoulder Pain: A Systematic Review.

Chau JPC, Lo SHS, Yu X, Choi KC, Lau AYL, Wu JCY, Lee VWY, Cheung WHN, Ching JYL, Thompson DR.
Front Neurol. 2018 Jan 31;9:30. doi: 10.3389/fneur.2018.00030. eCollection 2018.
Cognitive Disorders

White Matter Hyperintensity Predicts the Risk of Incident Cognitive Decline in Community Dwelling Elderly

Ding D, Xiong Y, Zhao Q, Guo Q, Chu S, Chu WWC, Luo J, Liang X, Zheng L, Hong Z, Wong LKS, Mok VCT.
J Alzheimers Dis. 2018;61(4):1333-1341. doi: 10.3233/JAD-170876.
Stroke & Cerebrovascular Diseases

Morphological Evolution or Symptomatic Irltracranial A herosclerotic Plaques: a 10-year Longitudinal Study by 3-Dimensional Rotational Angiography

Leng XY, Wang L, Zou XY, Soo YOY, Chan AYY, Ip VHL, Fan FSY, Mok CT, Wong LKS, Yu SCH, Leung TWH.
Stroke. 2018;49:A86.
Stroke & Cerebrovascular Diseases

Morphology of Acute Symptomatic Intracranial Atherosclerotic Plaques

Leng XY, Wang L, Zou XY, Soo YOY, Chan AYY, Ip VHL, Fan FSY, Mok CT, Wong LKS, Yu SCH, Leung TWH.
Stroke. 2018;49:ATP127.
Stroke & Cerebrovascular Diseases

Postmortem Study Exploring Distribution and Patterns of Intracranial Arterial Calcification.

Yang WJ, Zheng L, Wu XH, Niu CB, W Leung TW, Chen XY.
Stroke. 2018;49:AWMP44.
Stroke & Cerebrovascular Diseases

Use of Acupuncture to Reduce Hemiplegic Shoulder Pain is Feasible and Acceptable among Community-Dwelling Stroke Survivors.

Chau JPC, Lo SHS, Lau AYL, Wu JCY, Cheung WHN, Ching JYL, Choi KC, Lee VWY, Sit JWH, Thompson DR.
Stroke. 2018;49:ATP152.
Others

Estimating current and long-term risks of coronary artery in silico by fractional flow reserve, wall shear stress and low-density lipoprotein filtration rate

Haipeng Liu1,2,5, Yinglan Gong3,5, Xinyi Leng1, Ling Xia3, Ka Sing Wong1, Shanxing Ou4, Thomas W Leung1,6, Defeng Wang2 and Lin Shi2,6
Biomedical Physics & Engineering Express. 2018 Jan;4(2).
Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders

Preliminary Results of An Observational Study to Evaluate Integrative Medicine in Managing Fatigue and Cognitive Deficits Associated with Multiple Sclerosis

Ng A, Lam M, Au C, Yuen D, Cheung W, Hung Z, Lin WL, Chung V, Wong A, Chan J, Poon S, Poon J, Mok V, Wu J, Lau A.
Mult Scler J. 2018; 402-403.
Cognitive Disorders

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O7, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM5, Mattsson N7, Kornhuber J, Sabri O, Rowe CC, Parnetti L, Popp J, Fladby T, Jagust WJ5, Aalten P1, Lee DY, Vandenberghe R, Resende de Oliveira C, Kapaki E, Froelich L, Ivanoiu A, Gabryelewicz T, Verbeek MM, Sanchez-Juan P, Hildebrandt H, Camus V, Zboch M, Brooks DJ, Drzezga A, Rinne JO, Newberg A, de Mendonça A, Sarazin M, Rabinovici GD, Madsen K, Kramberger MG, Nordberg A, Mok V, Mroczko B, Wolk DA, Meyer PT, Tsolaki M, Scheltens P, Verhey FRJ, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BNM3, Blennow K, van Buchem MA, Cavedo E, Chen K, Chipi E, Cohen AD, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Gkatzima O, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Johannsen P, Klimkowicz-Mrowiec A, Köhler S, Koglin N, van Laere K, de Leon M, Lisetti V, Maier W, Marcusson J, Meulenbroek O, Møllergård HM, Morris JC, Nordlund A, Novak GP, Paraskevas GP, Perera G, Peters O, Ramakers IHGB, Rami L, Rodríguez-Rodríguez E, Roe CM, Rot U, Rüther E, Santana I, Schröder J, Seo SW, Soininen H, Spiru L, Stomrud E, Struyfs H, Teunissen CE8, Vos SJB, van Waalwijk van Doorn LJC, Waldemar G, Wallin ÅK, Wiltfang J, Zetterberg H.
JAMA Psychiatry. 2018 Jan 1;75(1):84-95. doi: 10.1001/jamapsychiatry.2017.3391.
Stroke & Cerebrovascular Diseases

Autonomic Dysfunction Predicts Clinical Outcomes After Acute Ischemic Stroke: A Prospective Observational Study.

Xiong L, Tian G, Leung H, Soo YOY, Chen X, Ip VHL, Mok VCT, Chu WCW, Wong KS, Leung TWH.
Stroke. 2018 Jan;49(1):215-218. doi: 10.1161/STROKEAHA.117.019312. Epub 2017 Dec 4.
Others

Impact of Side Branches on the Computation of Fractional Flow in Intracranial Arterial Stenosis Using the Computational Fluid Dynamics Method.

Liu H, Lan L, Leng X, Ip HL, Leung TWH, Wang D, Wong KS.
J Stroke Cerebrovasc Dis. 2018 Jan;27(1):44-52. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.032. Epub 2017 Oct 27.

2017

Stroke & Cerebrovascular Diseases

Cerebral perfusion difference between hemispheres with symptomatic and asymptomatic intracranial arterial stenosis.

Lan L, Leng X, Abrigo J, Ip V, Soo YO, Leung T, Chen X, Wong KS.
Int J Stroke. 2017 Dec;12(9):NP19-NP20. doi: 10.1177/1747493016676284. Epub 2016 Oct 20.
Stroke & Cerebrovascular Diseases

Brain microbleeds, anticoagulation, and hemorrhage risk: Meta-analysis in stroke patients with AF.

Charidimou A, Karayiannis C, Song TJ, Orken DN, Thijs V, Lemmens R, Kim J, Goh SM, Phan TG, Soufan C, Chandra RV, Slater LA, Haji S, Mok V, Horstmann S, Leung KT, Kawamura Y, Sato N, Hasebe N, Saito T, Wong LKS, Soo Y, Veltkamp R, Flemming KD, Imaizumi T, Srikanth V, Heo JH
Neurology. 2017 Dec 5;89(23):2317-2326. doi: 10.1212/WNL.0000000000004704.
Stroke & Cerebrovascular Diseases

Enlarged perivascular spaces are associated with health-related quality of life in patients with acute ischemic stroke.

Liang Y, Deng M, Chen YK, Mok V, Wang DF, Ungvari GS, Chu CW, Berge E, Tang WK
CNS Neurosci Ther. 2017 Dec;23(12):973-979. doi: 10.1111/cns.12766.
Cognitive Disorders

Minimum Clinically Important Difference of Montreal Cognitive Assessment in aneurysmal subarachnoid hemorrhage patients.

Wong GKC, Mak JSY, Wong A, Zheng VZY, Poon WS, Abrigo J, Mok VCT.
J Clin Neurosci. 2017 Dec;46:41-44. doi: 10.1016/j.jocn.2017.08.039. Epub 2017 Sep 5.
Parkinson’s Disease & Movement Disorders

Early versus Late Application of Subthalamic deep brain Stimulation to Parkinson's disease patients with motor complications (ELASS): protocol of a multicentre, prospective and observational study.

Jiang L, Poon WS, Moro E, Xian W, Yang C, Zhu XL, Gu J, Cai X, Liu J, Mok V, Liu Y, Xu S, Guo Q, Chen W, Chen L
BMJ Open. 2017 Nov 16;7(11):e018610. doi: 10.1136/bmjopen-2017-018610.
Others

The Spatial Associations of Cerebral Blood Flow and Spontaneous Brain Activities with White Matter Hyperintensities-An Exploratory Study Using Multimodal Magnetic Resonance Imaging.

Shi L, Miao X, Lou W, Liu K, Abrigo J, Wong A, Chu WCW, Wang D, Mok VCT.
Front Neurol. 2017 Nov 9;8:593. doi: 10.3389/fneur.2017.00593. eCollection 2017.
Cognitive Disorders

Using Retinal Imaging to Study Dementia.

Chan VTT, Tso THK, Tang F, Tham C, Mok V, Chen C, Wong TY, Cheung CY
J Vis Exp. 2017 Nov 6;(129). doi: 10.3791/56137.
Stroke & Cerebrovascular Diseases

Association of Cerebral Small Vessel Disease Burden and Health-Related Quality of Life after Acute Ischemic Stroke.

Liang Y, Chen YK, Deng M, Mok VCT, Wang DF, Ungvari GS, Chu CW, Kamiya A, Tang WK.
Front Aging Neurosci. . 2017 Nov 13;9:372. doi: 10.3389/fnagi.2017.00372. eCollection 2017.
Others

Current status of home blood pressure monitoring in Asia: Statement from the HOPE Asia Network

Chia YC1, Buranakitjaroen P, Chen CH, Divinagracia R, Hoshide S, Park S, Shin J, Siddique S, Sison J, Soenarta AA, Sogunuru GP, Tay JC, Turana Y, Wang JG, Wong L, Zhang Y, Kario K; HOPE Asia Network
J Clin Hypertens (Greenwich). 2017 Nov;19(11):1192-1201. doi: 10.1111/jch.13058. Epub 2017 Aug 17.
Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders

Cognitive profiles in Hong Kong Chinese with relapsing and progressive multiple sclerosis.

Lau AY, Ng A, Au C, Yuen KY, Mok V, Wu JC, Wong A.
MULT SCLER J. 2017 Oct; 23:764.
Stroke & Cerebrovascular Diseases

A retrospective, cross sectional controlled study of Chinese medicine for post-stroke rehabilitation.

Ma CH, Li LSW, Kwok LP, Tsang KWY, Cheng MCK, Mok VCT, Or KKH, Zhang ZJ.
J Neurol Sci. 2017 OCT 15;381:923.
Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders

Prevalence of neutralising antibodies to interferon-beta and clinical response in Chinese patients with relapsing multiple sclerosis.

Lau AY, Ip WK, Au C, Lau KK, Wong W, Yip KK, Yeung J, Li SH, Li P, Lee R, Siu D, Abrigo J, Wong A, Mok V, Chan E.
Mult Scler J Exp Transl Clin. 2017 Oct 9;3(4):2055217317733485. doi: 10.1177/2055217317733485. eCollection 2017 Oct-Dec.
Stroke & Cerebrovascular Diseases

Noninvasive fractional flow in intracranial atherosclerotic stenosis: Reproducibility, limitations, and perspectives.

Leng X, Lan L, Ip VHL, Liu H, Abrigo J, Liebeskind DS, Wong LKS, Leung TW.
J Neurol Sci. 2017 Oct 15;381:150-152. doi: 10.1016/j.jns.2017.08.3239. Epub 2017 Aug 24.
Stroke & Cerebrovascular Diseases

Smartphone electrographic monitoring for atrial fibrillation in acute ischemic stroke and transient ischemic attack

Tu HT, Chen Z, Swift C, Churilov L, Guo R, Liu X, Jannes J, Mok V, Freedman B, Davis SM, Yan B.
Int J Stroke. 2017 Oct;12(7):786-789. doi: 10.1177/1747493017696097. Epub 2017 Mar 8.
Cognitive Disorders
 
Stroke & Cerebrovascular Diseases

Development and validation of a risk score (CHANGE) for cognitive impairment after ischemic stroke.

Chander RJ, Lam BYK, Lin X, Ng AYT, Wong APL, Mok VCT, Kandiah N
Sci Rep. 2017 Sep 29;7(1):12441. doi: 10.1038/s41598-017-12755-z.
Stroke & Cerebrovascular Diseases

Histological Characteristics of Intracranial Atherosclerosis in a Chinese Population: A Postmortem Study.

Yang WJ, Fisher M, Zheng L, Niu CB, Paganini-Hill A, Zhao HL, Xu Y, Wong KS, NG HK, Chen XY.
Front Neurol. 2017;8:488.
Stroke & Cerebrovascular Diseases

Age-specific trends of atrial fibrillation-related ischaemic stroke and transient ischaemic attack, anticoagulant use and risk factor profile in Chinese population: a 15-year study.

Soo Y, Chan N, Leung KT, Chen XY, Mok V, Wong L, Leung T
J Neurol Neurosurg Psychiatry. 2017 Sep;88(9):744-748. doi: 10.1136/jnnp-2017-315735.
Cognitive Disorders

Recall Tests Are Effective to Detect Mild Cognitive Impairment: A Systematic Review and Meta-analysis of 108 Diagnostic Studies.

Tsoi KKF, Chan JYC, Hirai HW, Wong A, Mok VCT, Lam LCW, Kwok TCY, Wong SYS.
J Am Med Dir Assoc. 2017 Sep 1;18(9):807.e17-807.e29. doi: 10.1016/j.jamda.2017.05.016. Epub 2017 Jul 25.
Stroke & Cerebrovascular Diseases

Intracranial Atherosclerosis: From Microscopy to High-Resolution Magnetic Resonance Imaging.

Yang WJ, Wong KS, Chen XY.
J Stroke. 2017 Sep;19(3):249-260. doi: 10.5853/jos.2016.01956. Epub 2017 Sep 6.
Cognitive Disorders

Computerized Cognitive Screen (CoCoSc): A Self-Administered Computerized Test for Screening for Cognitive Impairment in Community Social Centers.

Wong A, Fong CH, Mok VC, Leung KT, Tong RK
J Alzheimers Dis. 2017;59(4):1299-1306. doi: 10.3233/JAD-170196.
Others

Using Large-Scale Statistical Chinese Brain Template (Chinese2020) in Popular Neuroimage Analysis Toolkits

Shi L, Liang PP, Luo Y, Liu K, Mok VCT, Chu WCW, Wang DF, Li KC.
Frontiers in Human Neuroscience. 2017;11:6.
Stroke & Cerebrovascular Diseases

Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries

Hilal S1, Mok V, Youn YC, Wong A, Ikram MK5, Chen CL
J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):669-674. doi: 10.1136/jnnp-2016-315324. Epub 2017 Jun 9.
Stroke & Cerebrovascular Diseases

Cortical Microinfarcts in Patients with Middle Cerebral Artery Stenosis.

Leng X, Fang H, Pu Y, Zou X, Pan Y, Soo YOY, Xu Y, Wang C, Zhao X, Wang Y, Wang Y, Liebeskind DS, Wong LKS, Leung TW6, Liu L.
J Stroke Cerebrovasc Dis. 2017 Aug;26(8):1760-1765. doi: 10.1016/j.jstrokecerebrovasdis.2017.04.002. Epub 2017 May 15.
Stroke & Cerebrovascular Diseases

External Counterpulsation Increases Beat-to-Beat Heart Rate Variability in Patients with Ischemic Stroke.

Xiong L1, Tian G, Wang L, Lin W, Chen X, Leung TWH, Soo YOY, Wong LKS.
J Stroke Cerebrovasc Dis. 2017 Jul;26(7):1487-1492. doi: 10.1016/j.jstrokecerebrovasdis.2017.03.007. Epub 2017 Apr 7.
Stroke & Cerebrovascular Diseases

Prediction of Recurrent Stroke or Transient Ischemic Attack After Noncardiogenic Posterior Circulation Ischemic Stroke.

Zhang C, Wang Y, Zhao X, Liu L, Wang C, Pu Y, Zou X, Pan Y, Wong KS, Wang Y; Chinese IntraCranial AtheroSclerosis (CICAS) Study Group.
Stroke. 2017 Jul;48(7):1835-1841. doi: 10.1161/STROKEAHA.116.016285. Epub 2017 Jun 16.
Stroke & Cerebrovascular Diseases

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org

Hoshino T, Uchiyama S, Wong LKS, Sissani L, Albers GW, Bornstein NM, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Labreuche J, Lavallée PC, Molina C, Rothwell PM, Steg PG, Touboul PJ, Vicaut É, Amarenco P; TIAregistry.org Investigators.
Stroke. 2017 Jul;48(7):1779-1787. doi: 10.1161/STROKEAHA.117.016874. Epub 2017 Jun 5.
Stroke & Cerebrovascular Diseases

Impaired cerebral autoregulation: measurement and application to stroke.

Xiong L, Liu X, Shang T, Smielewski P, Donnelly J, Guo ZN, Yang Y, Leung T, Czosnyka M, Zhang R, Liu J, Wong KS.
J Neurol Neurosurg Psychiatry. 2017 Jun;88(6):520-531. doi: 10.1136/jnnp-2016-314385.
Parkinson’s Disease & Movement Disorders

A Randomized Controlled Trial of Chinese Medicine on Nonmotor Symptoms in Parkinson's Disease

Ka-Kit Chua, Adrian Wong, Kam-Wa Chan, Yin-Kei Lau, Zhao-Xiang Bian, Jia-Hong Lu, Liang-Feng Liu, Lei-Lei Chen, Ka-Ho Chan, Kim-Pong Tse,1 Anne Chan, Ju-Xian Song, Justin Wu, Li-Xing Zhu, Vincent Mok, and Min Li1
Parkinsons Dis. 2017;2017:1902708.
Others

Excessive Daytime Sleepiness Predicts Neurodegeneration in Idiopathic REM Sleep Behavior Disorder.

Zhou J, Zhang J, Lam SP, Chan JW, Mok V, Chan A, Li SX4, Liu Y, Tang X, Yung WH, Wing YK
Sleep. 2017 May 1;40(5). doi: 10.1093/sleep/zsx041.
Stroke & Cerebrovascular Diseases

Is Dynamic Cerebral Autoregulation Bilaterally Impaired after Unilateral Acute Ischemic Stroke?

Xiong L, Tian G, Lin W, Wang W, Wang L, Leung T, Mok V, Liu J, Chen X, Wong KS
J Stroke Cerebrovasc Dis. 2017 May;26(5):1081-1087. doi: 10.1016/j.jstrokecerebrovasdis.2016.12.024.
Stroke & Cerebrovascular Diseases

Location of Acute Infarcts and Agitation and Aggression in Stroke

Tang WK, Liu XX, Liang H, Chen YK, Chu WCW, Ahuja AT, Abrigo J, Mok VCT, Ungvari GS, Wong KS, Spalletta G
J Neuropsychiatry Clin Neurosci. 2017 Spring;29(2):172-178. doi: 10.1176/appi.neuropsych.15110400.
Stroke & Cerebrovascular Diseases

Neuroticism and Fatigue 3 Months After Ischemic Stroke: A Cross-Sectional Study.

Lau CG, Tang WK, Liu XX, Liang HJ, Liang Y, Mok V, Wong A, Ungvari GS, Kutlubaev MA, Wong KS.
Arch Phys Med Rehabil. 2017 Apr;98(4):716-721. doi: 10.1016/j.apmr.2016.08.480. Epub 2016 Sep 24.
Stroke & Cerebrovascular Diseases

Intracranial atherosclerosis: From anatomy to pathophysiology.

Pu Y, Lan L, Leng X, Wong LK, Liu L.
Int J Stroke. 2017 Apr;12(3):236-245. doi: 10.1177/1747493016685716. Epub 2017 Jan 9.
Cognitive Disorders

Early-onset and delayed-onset poststroke dementia - revisiting the mechanisms.

Mok VC, Lam BY, Wong A, Ko H, Markus HS, Wong LK
Nat Rev Neurol. 2017 Mar;13(3):148-159. doi: 10.1038/nrneurol.2017.16.
Stroke & Cerebrovascular Diseases

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting.

Hobeanu C, Lavallée PC, Rothwell PM, Sissani L, Albers GW, Bornstein NM, Caplan LR, Donnan GA, Ferro JM, Hennerici MG, Labreuche J, Molina C, Steg PG, Touboul PJ, Uchiyama S, Vicaut É, Wong LK, Amarenco P; TIAregistry.org Investigators.
Stroke. 2017 Apr;48(4):1005-1010. doi: 10.1161/STROKEAHA.116.015171. Epub 2017 Mar 13.
Stroke & Cerebrovascular Diseases

Group comparison of cortical fiber connectivity map: An application between post-stroke patients and healthy subjects.

Liu K, Zhang T, Chu WC, Mok VC, Wang D, Shi L
Neuroscience. 2017 Mar 6;344:15-24. doi: 10.1016/j.neuroscience.2016.12.026.
Stroke & Cerebrovascular Diseases

Poststroke agitation and aggression and social quality of life: a case control study.

Lau CG, Tang WK, Liu XX, Liang HJ, Liang Y, Wong A, Mok V, Ungvari GS, Wong KS, Kim JS, Paradiso S.
Top Stroke Rehabil. 2017 Mar;24(2):126-133. doi: 10.1080/10749357.2016.1212564. Epub 2016 Sep 7.
Stroke & Cerebrovascular Diseases

Clinical Features of Thalamic Stroke

Chen XY, Wang Q, Wang X, Wong KS
Curr Treat Options Neurol . 2017 Feb;19(2):5. doi: 10.1007/s11940-017-0441-x.
Others

Limb girdle myasthenia with digenic RAPSN and a novel disease gene AK9 mutations

Lam CW, Wong KS, Leung HW, Law CY.
Eur J Hum Genet. 2017 Feb;25(2):192-199. doi: 10.1038/ejhg.2016.162. Epub 2016 Dec 14.
Stroke & Cerebrovascular Diseases

High Extent of Intracranial Carotid Artery Calcification Is Associated with Downstream Microemboli in Stroke Patients.

Wu XH, Chen XY, Fan YH, Leung TW, Wong KS.
J Stroke Cerebrovasc Dis. 2017 Feb;26(2):442-447. doi: 10.1016/j.jstrokecerebrovasdis.2016.10.007. Epub 2016 Nov 3.
Parkinson’s Disease & Movement Disorders

Cross-Cultural Differences of the Non-Motor Symptoms Studied by the Traditional Chinese Version of the International Parkinson and Movement Disorder Society- Unified Parkinson's Disease Rating Scale.

Yu RL1, Wu RM, Chan AY, Mok V, Wu YR, Tilley BC, Luo S, Wang L, LaPelle NR, Stebbins GT, Goetz CG
Mov Disord Clin Pract. 2017 Jan-Feb;4(1):68-77. doi: 10.1002/mdc3.12349.
Parkinson’s Disease & Movement Disorders

Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study.

Wang L, Heckman MG, Aasly JO, Annesi G, Bozi M, Chung SJ, Clarke C, Crosiers D, Eckstein G, Garraux G, Hadjigeorgiou GM, Hattori N, Jeon B, Kim YJ, Kubo M, Lesage S, Lin JJ, Lynch T, Lichtner P, Mellick GD, Mok V, Morrison KE, Quattrone A, Satake W, Silburn PA, Stefanis L, Stockton JD, Tan EK, Toda T, Brice A, Van Broeckhoven C, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, Gasser T, Krüger R, Farrer MJ, Ross OA, Sharma M
Neurobiol Aging. 2017 Jan;49:217.e1-217.e4. doi: 10.1016/j.neurobiolaging.2016.09.022.
Parkinson’s Disease & Movement Disorders

Genome-wide association study of Parkinson's disease in East Asians.

Foo JN, Tan LC, Irwan ID, Au WL, Low HQ, Prakash KM, Ahmad-Annuar A, Bei J, Chan AY, Chen CM, Chen YC, Chung SJ, Deng H, Lim SY, Mok V, Pang H, Pei Z, Peng R, Shang HF, Song K, Tan AH, Wu YR, Aung T, Cheng CY, Chew FT, Chew SH, Chong SA, Ebstein RP, Lee J, Saw SM, Seow A, Subramaniam M, Tai ES, Vithana EN, Wong TY, Heng KK, Meah WY, Khor CC, Liu H, Zhang F, Liu J, Tan EK
Hum Mol Genet. 2017 Jan 1;26(1):226-232. doi: 10.1093/hmg/ddw379.
Others

Deep Cascaded Networks for Sparsely Distributed Object Detection from Medical Images

Chen, H Dou, Q Yu, L Qin, J Zhao, L Mok, VCT Wang, D Shi, L Heng, PA
Deep Learning for Medical Image Analysis. 2017:(6):133-135.
Stroke & Cerebrovascular Diseases
 
Cognitive Disorders

A 5-Year Longitudinal Study of Cognitive Decline After Stroke/Transient Ischemic Attack (CU-STRIDE).

Lam B, Wong A, Wang ZL, Liu WY, Au L, Chan A, Lau A, Shi L, Fan F, Ma SH, Ip V, Soo Y, Leung T, Leng XY, Chen XY, Chu W, Mok V.
Cerebrovasc Dis. 2017;44(S1):4.
Stroke & Cerebrovascular Diseases

Prolonged Perfusion Predicts Recurrent Ischemic Stroke but not Transient Ischemic Attack in Patients with Symptomatic Intracranial Stenosis.

Lan L, Leng X, Ip V, Leung T, Soo Y, Abrigo J, Wong KS.
Curr Neurovasc Res. 2017;14(2):149-157. doi: 10.2174/1567202614666170413143203.
Stroke & Cerebrovascular Diseases

The prognosis of acute symptomatic seizures after ischaemic stroke.

Leung T, Leung H, Soo YO, Mok VC, Wong KS.
J Neurol Neurosurg Psychiatry. 2017 Jan;88(1):86-94. doi: 10.1136/jnnp-2015-311849. Epub 2016 Jan 27.
Stroke & Cerebrovascular Diseases

Benign Oligemia in Subacute Stage Is Associated with Borderzone Infarction in Stroke Patients Caused by Intracranial Large Artery Disease

Li J, Chen XY, Soo Y, Leung TW, Zeng J, Wong KS.
Eur Neurol. 2017;77(1-2):80-86. doi: 10.1159/000454678. Epub 2016 Dec 14.
Others

Morphometry analysis of basal ganglia structures in children with obstructive sleep apnea.

Lv J, Shi L, Zhao L, Weng J, Mok VC, Chu WC, Wang D.
J Xray Sci Technol. 2017;25(1):93-99. doi: 10.3233/XST-16171.
Stroke & Cerebrovascular Diseases

Sex Differences Do Not Exist in Outcomes among Stroke Patients with Intracranial Atherosclerosis in China: Subgroup Analysis from the Chinese Intracranial Atherosclerosis Study

Pu Y, Wei N, Yu D, Wang Y, Zou X, Soo YOY, Pan Y, Leung TWH, Wong LKS, Wang Y, Liu L.
Neuroepidemiology. 2017;18(1-2):48-54.
Stroke & Cerebrovascular Diseases

Association studies of genetic polymorphism and environmental factors in ischemic stroke with atherosclerotic middle cerebral artery stenosis.

Zhang ZS, Chen XY, Baum L, Ng HK, Mok V, Wong KS.
Neurology Asia. 2017;22(4):291-297.