People
Dr. Howan LEUNG
The Chinese University of Hong Kong
Head of Division of Neurology (Clinical Service)
Clinical Associate Professor (honorary), Department of Medicine & Therapeutics
Head of Epilepsy and Electrodiagnostic Unit, Division of Neurology
Prince of Wales Hospital
Consultant, Department of Medicine & Therapeutics
Academic and Professional Qualifications
MBBS, MRCP (UK), FHKCP, FHKAM (Medicine)Biography
Dr Leung is a neurologist by training. He completed overseas studies in Bonn, Germany. Afterwards he helped pioneer multimodal investigations in refractory epilepsy and successfully renewed collaborations with other neuroscience partners for the betterment of epilepsy patients. His interests included among others different diagnostics: conventional electroencephalography(EEG), high-density EEG, intracranial EEG, stereo-EEG, ambulatory EEG and high frequency oscillations. In 2019, he received a first class award in science and technology progress from the Ministry of Education of China. In 2025, he and together with the Department of Neurosurgery and Department of Paediatrics, successfully completed the epilepsy accreditation from China Association Against Epilepsy (CAAE).
Dr. Howan LEUNG
The Chinese University of Hong Kong
Head of Division of Neurology (Clinical Service)
Clinical Associate Professor (honorary), Department of Medicine & Therapeutics
Head of Epilepsy and Electrodiagnostic Unit, Division of Neurology
Prince of Wales Hospital
Consultant, Department of Medicine & Therapeutics
Research Interests
- Electroencephalography
- Pre-surgical evaluation of refractory epilepsy
- Epidemiology and drug treatment of epilepsy
Professional Service
- Past President of Hong Kong Epilepsy Society
- Member of CAAE (China Association Against Epilepsy)
- Scientific Organization Committee Member of Asian Oceanian Epilepsy Congress in 2025
- Member of the Sub-committee on treatment and rehabilitation of the Action Committee Against Narcotics
- Member of Elderly Persons Commission by International League Against Epilepsy
- Chairman of Electrophysiology Subcommittee of Hong Kong Neurological Society 2025
- Board member of Specialty Neurology Board, Hong Kong College of Physicians 2013-2017
Awards
- Accreditation of comprehensive epilepsy centre by China Association Against Epilepsy 2025
- Outstanding team (New Territories East Cluster) on functional neuroscience, Hospital Authority 2024
- First class award in science and technology progress, Ministry of Education Higher Education Outstanding Scientific Research Output Awards 2019
Selected Publications
- Wang L, Kong Q, Leng X, Leung H, Li Y. The sphingosine-1-phosphate signaling pathway (sphingosine-1-phosphate and its receptor, sphingosine kinase) and epilepsy. Epilepsia Open. 2025 Feb;10(1):55-73. doi: 10.1002/epi4.13112. Epub 2024 Dec 27. PMID: 39727628; PMCID: PMC11803289.
- Ip BY, Ko H, Wong GL, Yip TC, Lau LH, Lau AY, Leng X, Leung H, Chan HH, Chan HY, Mok VC, Soo YO, Leung TW. Thromboembolic Risks with Concurrent Direct Oral Anticoagulants and Antiseizure Medications: A Population-Based Analysis. CNS Drugs. 2022 Dec;36(12):1313-1324. doi: 10.1007/s40263-022-00971-9. Epub 2022 Nov 24. PMID: 36424415; PMCID: PMC9712286.
- Niyongere J, Welty TE, Bell MW, Consalvo D, Hammond C, Leung H, Patsalos PN, Ryan M, Suansanae T, Zhou D, Zuellig H. Barriers to generic antiseizure medication use: Results of a global survey by the International League Against Epilepsy Generic Substitution Task Force. BEpilepsia Open. 2022 Jun;7(2):260-270. doi: 10.1002/epi4.12583. Epub 2022 Feb 18. PMID: 35124903; PMCID: PMC9159248.
- Chang X, Yao S, Wei J, Shang L, Xu C, Ma J. The validation and cross-cultural adaptation of the PainDETECT questionnaire in osteoarthritis-related pain J Orthop Surg Res. 2025 Jan 24;20(1):94. doi: 10.1186/s13018-025-05510-y. PMID: 39849547; PMCID: PMC11758734.
- Yip KL, Zhou X, Chook P, Leung PC, Schachter S, Mok VCT, Leung TWH, Koon CM, Leung H. Herb-drug interaction of gastrodiae rhizoma on carbamazepine: A pharmacokinetic study in rats. Epilepsy Res. 2020 Sep;165:106376. doi: 10.1016/j.eplepsyres.2020.106376. Epub 2020 May 31. PMID: 32526641
- Yip KL, Koon CM, Chen ZY, Chook P, Leung PC, Schachter S, Leung WH, Mok CT, Leung H. The antiepileptic effect of Gastrodiae Rhizoma through modulating overexpression of mTOR and attenuating astrogliosis in pilocarpine mice model Epilepsia Open. 2019 Dec 13;5(1):50-60. doi: 10.1002/epi4.12372. PMID: 32140643; PMCID: PMC7049815.
- Leung HW, Poon WS, Kwan PK, Lui CH, Poon TL, Chan EL, Yuen SC. Ictal intracranial electroencephalography using wavelet analysis of high-frequency oscillations in Chinese patients with refractory epilepsy. Hong Kong Med J. 2018 Jun;24 Suppl 3(3):21-23. PMID: 29937441.
- Tsai JJ, Wu T, Leung H, Desudchit T, Tiamkao S, Lim KS, Dash A. Perampanel, an AMPA receptor antagonist: From clinical research to practice in clinical settings. Acta Neurol Scand. 2018 Apr;137(4):378-391. doi: 10.1111/ane.12879. Epub 2017 Dec 7. PMID: 29214650.
- Leung T, Leung H, Soo YO, Mok VC, Wong KS. The prognosis of acute symptomatic seizures after ischaemic stroke. J Neurol Neurosurg Psychiatry. 2017 Jan;88(1):86-94. doi: 10.1136/jnnp-2015-311849. Epub 2016 Jan 27. PMID: 26818728.